Abstract Background Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, also referred to
as Müllerian aplasia, is a congenital disorder characterized by aplasia of the uterus and …

BACKGROUND Infertility is a major issue in human reproductive health, affecting an
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …

The WNT signal transduction cascade controls myriad biological phenomena throughout
development and adult life of all animals. In parallel, aberrant Wnt signaling underlies a …

Background Disorders of sex development (DSD) are congenital conditions in which
chromosomal, gonadal, or phenotypic sex is atypical. Clinical management of DSD is often …

The primary causes of chronic kidney disease (CKD) in children differ from those of CKD in
adults. In the USA the most common diagnostic groups of renal disease that manifest before …

Signaling by the Wnt family of secreted glycolipoproteins via the transcriptional coactivator β-
catenin controls embryonic development and adult homeostasis. Here we review recent …

Background Congenital anomalies of the kidney and urinary tract (CAKUT) are the most
prevalent cause of kidney disease in the first three decades of life. Previous gene panel …

Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome, also referred to as Müllerian
agenesis, is the second most common cause of primary amenorrhea. It is characterized by …

Abstract The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is characterized by
congenital aplasia of the uterus and the upper part (2/3) of the vagina in women showing …

Congenital anomalies of the kidney and urinary tract (CAKUT) cover a wide range of
structural malformations that result from defects in the morphogenesis of the kidney and/or …