[HTML][HTML] Sensorimotor integration in childhood dystonia and dystonic cerebral palsy—a developmental perspective

VM McClelland, JP Lin - Frontiers in Neurology, 2021 - frontiersin.org
Dystonia is a disorder of sensorimotor integration, involving dysfunction within the basal
ganglia, cortex, cerebellum, or their inter-connections as part of the sensorimotor network …

Locomotion is impacted differently according to the perinatal brain injury model: Meta-analysis of preclinical studies with implications for cerebral palsy

S da Conceição Pereira, R Manhães-de-Castro… - Journal of Neuroscience …, 2021 - Elsevier
Background Different approaches to reproduce cerebral palsy (CP) in animals, contribute to
the knowledge of the pathophysiological mechanism of this disease and provide a basis for …

[HTML][HTML] Early movement restriction leads to maladaptive plasticity in the sensorimotor cortex and to movement disorders

M Delcour, M Russier, F Castets, N Turle-Lorenzo… - Scientific reports, 2018 - nature.com
Motor control and body representations in the central nervous system are built, ie, patterned,
during development by sensorimotor experience and somatosensory feedback/reafference …

Motor deficits are associated with increased glial cell activation in the hypothalamus and cerebellum of young rats subjected to cerebral palsy

BJR Costa-de-Santana, R Manhães-de-Castro… - Brain Research, 2023 - Elsevier
Cerebral palsy (CP) is a syndrome characterized by a wide range of sensory and motor
damage, associated with behavioral and cognitive deficits. The aim of the present study was …

Early neurodevelopmental reflex impairments in a rodent model of cerebral palsy

D Ho, EF Sanches… - International Journal of …, 2022 - Wiley Online Library
Cerebral palsy (CP) causes sensorimotor disabilities due to injury to the developing brain.
Experimental models do not always induce the CP phenotype completely. Early …

[HTML][HTML] Early movement restriction affects the acquisition of neurodevelopmental reflexes in rat pups

O Dupuis, M Van Gaever, V Montel, J Dereumetz… - Brain research, 2024 - Elsevier
Childhood is a period of construction of the organism, during which interactions with the
environment and regular physical activity are necessary for the maturation of the neuronal …

Early intensive rehabilitation reverses locomotor disruption, decrease brain inflammation and induces neuroplasticity following experimental Cerebral Palsy

E Sanches, HO Dini, Y van de Looij, AA Toulotte… - Brain, Behavior, and …, 2024 - Elsevier
Abstract Background Cerebral Palsy (CP) is a major cause of motor and cognitive disability
in children due to injury to the developing brain. Early intensive sensorimotor rehabilitation …

Neonatal kaempferol exposure attenuates gait and strength deficits and prevents altered muscle phenotype in a rat model of cerebral palsy

DB Visco, R Manhães de Castro… - International Journal …, 2023 - Wiley Online Library
Cerebral palsy (CP) is characterized by brain damage at a critical period of development of
the central nervous system, and, as a result, motor, behavioural and learning deficits are …

Creatine supplementation increases postnatal growth and strength and prevents overexpression of pro-inflammatory interleukin 6 in the hippocampus in an …

HJCB Gouveia, R Manhães-de-Castro… - Nutritional …, 2024 - Taylor & Francis
Objectives: The aim of this study was thus to evaluate the effect of Cr supplementation on
morphological changes and expression of pro-inflammatory cytokines in the hippocampus …

Experimental cerebral palsy causes microstructural brain damage in areas associated to motor deficits but no spatial memory impairments in the developing rat

EF Sanches, AS Carvalho, Y van de Looij, A Toulotte… - Brain Research, 2021 - Elsevier
Introduction Cerebral palsy (CP) is the major cause of motor and cognitive impairments
during childhood. CP can result from direct or indirect structural injury to the developing …