Palladium catalyzed C–C and C–N bond forming reactions: an update on the synthesis of pharmaceuticals from 2015–2020

J Rayadurgam, S Sana, M Sasikumar… - Organic Chemistry …, 2021 - pubs.rsc.org
Some of the most prominent and promising catalysts in organic synthesis for the requisite
construction of C–C and C–N bonds are palladium (Pd) catalysts, which play a pivotal role in …

Recent applications of palladium‐catalyzed coupling reactions in the pharmaceutical, agrochemical, and fine chemical industries

C Torborg, M Beller - Advanced Synthesis & Catalysis, 2009 - Wiley Online Library
Palladium‐catalyzed coupling reactions have become a central tool for the synthesis of
biologically active compounds both in academia and industry. Most of these transformations …

Few-layer graphdiyne doped with sp-hybridized nitrogen atoms at acetylenic sites for oxygen reduction electrocatalysis

Y Zhao, J Wan, H Yao, L Zhang, K Lin, L Wang… - Nature …, 2018 - nature.com
The oxygen reduction reaction (ORR) is a fundamental reaction for energy storage and
conversion. It has mainly relied on platinum-based electrocatalysts, but the chemical doping …

Copper-free Sonogashira cross-coupling reactions: an overview

F Mohajer, MM Heravi, V Zadsirjan… - RSC advances, 2021 - pubs.rsc.org
The Sonogashira reaction is a cross-coupling reaction of a vinyl or aryl halide with a terminal
alkyne to form a C–C bond. In its original form, the Sonogashira reaction is performed with a …

Kinetic isotope effects in the study of organometallic reaction mechanisms

M Gomez-Gallego, MA Sierra - Chemical reviews, 2011 - ACS Publications
Kinetic Isotope Effects in the Study of Organometallic Reaction Mechanisms | Chemical
Reviews ACS ACS Publications C&EN CAS Find my institution Log In Chemical Reviews ACS …

The Sonogashira reaction: a booming methodology in synthetic organic chemistry

R Chinchilla, C Nájera - Chemical reviews, 2007 - ACS Publications
The array of transition-metal-catalyzed cross-coupling reactions can easily be considered
nowadays cornerstones in the field of organic synthesis. 1, 2 Among them, the palladium …

Domino reactions in organic synthesis

LF Tietze - Chemical reviews, 1996 - ACS Publications
Synthetic organic chemistry has developed in a fascinating way over the past decades.
Several highly selective procedures have been developed which allow the preparation of …

C H Activation: A Complementary Tool in the Total Synthesis of Complex Natural Products

DYK Chen, SW Youn - Chemistry–A European Journal, 2012 - Wiley Online Library
The recent advent of transition‐metal mediated C H activation is revolutionizing the
synthetic field and gradually infusing a “C H activation mind‐set” in both students and …

Palladium and copper catalyzed Sonogashira cross coupling an excellent methodology for CC bond formation over 17 years: A review

I Kanwal, A Mujahid, N Rasool, K Rizwan, A Malik… - Catalysts, 2020 - mdpi.com
Sonogashira coupling involves coupling of vinyl/aryl halides with terminal acetylenes
catalyzed by transition metals, especially palladium and copper. This is a well known …

Palladium‐based catalytic systems for the synthesis of conjugated enynes by Sonogashira reactions and related alkynylations

H Doucet, JC Hierso - Angewandte Chemie International …, 2007 - Wiley Online Library
Conjugated alkynes are recurring building blocks in natural products, a wide range of
industrial intermediates, pharmaceuticals and agrochemicals, and molecular materials for …