Compounds incorporating the chromene scaffold are largely present in natural products and
display a wide variety of biological activities. Their low toxicity combined to the broad …

Alzheimer's disease (AD) is a complex and progressive neurodegenerative disorder. The
available therapy is limited to the symptomatic treatment and its efficacy remains …

Alzheimer's disease is a multifactorial and fatal neurodegenerative disorder characterized
by decline of cholinergic function, deregulation of other neurotransmitter systems, β-amyloid …

Abstract ortho-Quinone methides are useful transient synthetic intermediates in organic
synthesis. These species are most often generated in situ by the acid-or base-mediated …

Novel tacrine-related drugs as potential candidates for the treatment of Alzheimer’s disease -
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Quinoline analogs are an important class of N-based heterocyclic compounds, which have
received extensive attention because of their use in medicinal chemistry and organic …

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder. Several hallmarks
such as β-amyloid (Aβ) aggregation underlying amyloid plaque formation, Τ …

In the current scenario of medicinal chemistry, quinoline plays a pivotal role in the design of
new heterocyclic compounds with several pharmacological properties, so the search for new …

A series of biologically important 2-amino-4H-chromenes functionalized with different
substituents have been synthesized through a one-pot multicomponent reaction catalysed …

A streamlined method for the enantioselective synthesis of 2-amino-4 H-chromenes from
readily available 2-alkyl-substituted phenols and active methylene compounds bearing a …