Background Rectal cancer management has evolved into a complex multimodality approach
with survival, local recurrence, and quality of life parameters being the relevant endpoints …

The proximity of the very low rectum rectal cancer to the anal sphincter raises a specific
problem: how and until when can we preserve the anal continence without compromising …

Abstract RIO Kinase 1 (RIOK1) is involved in various pathologies, including cancer.
However, the role of RIOK1 in radioresistance of colorectal cancer (CRC) remains largely …

Aim The long‐term risk of definitive stoma after sphincter‐saving resection (SSR) for rectal
cancer is underestimated and has never been reported for ultralow conservative surgery …

A percentage of colorectal cancer (CRC) patients display low sensitivity to radiotherapy,
which affects its therapeutic effect. Cancer cells DNA double-strand breaks (DSBs) repair …

XRCC2 has been shown to increase the radioresistance of some cancers. Here, XRCC2
expression was investigated as a predictor of preoperative radiotherapy (PRT) treatment …

As is well known that colorectal cancer is the third most common cancer in the world, and
radiation treatment plays a vital role in colorectal cancer therapy, but radiation resistance is …

DNA is subject to a range of endogenous and exogenous insults that can impair DNA
replication and lead to DNA double-strand breaks (DSBs). The repair capacity of cancer …

Thieme E-Journals - Clinics in Colon and Rectal Surgery / Full Text DE EN Home Products
Journals Books Book Series Service Library Service Help Contact Portal Clinics in Colon and …

Background There is growing recognition for the consequences of rectal cancer treatment to
maintain an adequate functional sphincter in the long-term rather than preserving the anal …