Background. Alzheimer's disease (AD) is a progressive neurodegenerative disorder
affecting many individuals worldwide with no effective treatment to date. AD is characterized …

Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe.
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …

Immune cells react to their environment by flexibly reprogramming intracellular metabolic
pathways that subsequently alter immune function, in a process called immunometabolism …

Traumatic brain injury (TBI) is a growing health concern effecting civilians and military
personnel. Research has yielded a better understanding of the pathophysiology of TBI, but …

Imaging plays an essential role in identifying intracranial injury in patients with traumatic
brain injury (TBI). The goals of imaging include (1) detecting injuries that may require …

Concussion (mild traumatic brain injury [TBI]), particularly with organized sports, has come to
the forefront of popular culture. Affecting about 1.6 million to 3.8 million athletes a year, its …

Multi-modal biomarkers (eg, imaging, blood-based, physiological) of unique traumatic brain
injury (TBI) endophenotypes are necessary to guide the development of personalized and …

In the United States, traumatic brain injury (TBI) is estimated to affect 1.7 million people
annually, leading to approximately 52,000 deaths and 275,000 hospitalizations. TBI plays a …

Neurotransmitters are endogenous chemical messengers which play an important role in
many of the brain functions, abnormal levels being correlated with physical, psychotic and …

Abstract Purpose of Review The concussion public health burden has increased alongside
our knowledge of the pathophysiology of mild traumatic brain injury (mTBI). The purpose of …