How phages overcome the challenges of drug resistant bacteria in clinical infections

M Taati Moghadam, N Amirmozafari… - Infection and Drug …, 2020 - Taylor & Francis
Nowadays the most important problem in the treatment of bacterial infections is the
appearance of MDR (multidrug-resistant), XDR (extensively drug-resistant) and PDR (pan …

Bacteriophages, a new therapeutic solution for inhibiting multidrug-resistant bacteria causing wound infection: lesson from animal models and clinical trials

M Taati Moghadam, A Khoshbayan… - Drug design …, 2020 - Taylor & Francis
Wound infection kills a large number of patients worldwide each year. Staphylococcus
aureus, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa …

Evaluation of Nano-curcumin effects on expression levels of virulence genes and biofilm production of multidrug-resistant Pseudomonas aeruginosa isolated from …

A Shariati, E Asadian, F Fallah, T Azimi… - Infection and drug …, 2019 - Taylor & Francis
Background P. aeruginosa is considered as one of the most important pathogens, and high
antibiotic resistance to P. aeruginosa has become an alarming concern. This study attempts …

Evaluating the antimicrobial resistance patterns among major bacterial pathogens isolated from clinical specimens taken from patients in Mofid Children's Hospital …

T Azimi, S Maham, F Fallah, L Azimi… - Infection and drug …, 2019 - Taylor & Francis
Background This study evaluates the epidemiology and antimicrobial resistance profile of
Gram-negative bacteria (GNB) and Gram-positive bacteria (GPB) isolated from clinical …

The Global and Regional Prevalence of Hospital-Acquired Carbapenem-Resistant Klebsiella pneumoniae Infection: A Systematic Review and Meta-analysis

X Lin, C Li, S Zhang, X Yang… - Open Forum Infectious …, 2024 - academic.oup.com
Background Due to scarce therapeutic options, hospital-acquired infections caused by
Klebsiella pneumoniae (KP), particularly carbapenem-resistant KP (CRKP), pose enormous …

[HTML][HTML] Bacteriophage therapy for inhibition of multi drug‐resistant uropathogenic bacteria: a narrative review

Z Chegini, A Khoshbayan, S Vesal… - Annals of Clinical …, 2021 - Springer
Abstract Multi-Drug Resistant (MDR) uropathogenic bacteria have increased in number in
recent years and the development of new treatment options for the corresponding infections …

[HTML][HTML] In vitro antibacterial activity of curcumin-meropenem combination against extensively drug-resistant (XDR) bacteria isolated from burn wound infections

JY Sharahi, ZA Ahovan, DT Maleki… - Avicenna journal of …, 2020 - ncbi.nlm.nih.gov
Objective: Burn wound infection is a severe complication of thermal injury. Patients with
severe burn injuries need urgent care to diminish complications after severe burns. Wound …

[HTML][HTML] Phage therapy, a salvage treatment for multidrug-resistant bacteria causing infective endocarditis

HF Hetta, ZI Rashed, YN Ramadan, IMS Al-Kadmy… - Biomedicines, 2023 - mdpi.com
Infective endocarditis (IE) is defined as an infection of the endocardium, or inner surface of
the heart, most frequently affecting the heart valves or implanted cardiac devices. Despite its …

[HTML][HTML] PATTERNS OF ANTIMICROBIAL RESISTANCE AMONG MAJOR BACTERIAL PATHOGENS ISOLATED FROM CLINICAL SAMPLES IN TWO TERTIARY'S …

HZ Al-Shami, MA Al-Haimi, OAE Al-dossary… - Universal Journal of …, 2021 - ujpronline.com
Background and objectives: At the present time, antimicrobial resistance (AMR) is a major
public health hazard, with antimicrobial resistance bacteria increasing exponentially. This …

[HTML][HTML] Evaluating the antimicrobial resistance patterns and molecular frequency of blaoxa-48 and blaGES-2 genes in Pseudomonas aeruginosa and Acinetobacter …

F Tarafdar, B Jafari, T Azimi - New Microbes and New Infections, 2020 - Elsevier
The aim of this study is to evaluate the antimicrobial resistance patterns and molecular
frequency of bla GES-2 and bla oxa-48 genes in Pseudomonas aeruginosa and …