[HTML][HTML] Ultrasound elastography: review of techniques and clinical applications
RMS Sigrist, J Liau, A El Kaffas, MC Chammas… - Theranostics, 2017 - ncbi.nlm.nih.gov
Elastography-based imaging techniques have received substantial attention in recent years
for non-invasive assessment of tissue mechanical properties. These techniques take …
for non-invasive assessment of tissue mechanical properties. These techniques take …
Approved antiviral drugs over the past 50 years
E De Clercq, G Li - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …
categorized into 13 functional groups have been formally approved for the treatment of the …
Hepatitis C virus infection
MP Manns, M Buti, ED Gane, JM Pawlotsky… - Nature reviews Disease …, 2017 - nature.com
Hepatitis C virus (HCV) is a hepatotropic RNA virus that causes progressive liver damage,
which might result in liver cirrhosis and hepatocellular carcinoma. Globally, between 64 and …
which might result in liver cirrhosis and hepatocellular carcinoma. Globally, between 64 and …
Glecaprevir and pibrentasvir in patients with HCV and severe renal impairment
E Gane, E Lawitz, D Pugatch… - … England Journal of …, 2017 - Mass Medical Soc
Background Chronic hepatitis C virus (HCV) infection is more prevalent among patients who
have chronic kidney disease than among those who do not have the disease. Patients with …
have chronic kidney disease than among those who do not have the disease. Patients with …
Glecaprevir plus pibrentasvir for chronic hepatitis C virus genotype 1, 2, 4, 5, or 6 infection in adults with compensated cirrhosis (EXPEDITION-1): a single-arm, open …
X Forns, SS Lee, J Valdes, S Lens, R Ghalib… - The Lancet infectious …, 2017 - thelancet.com
Background The once-daily, ribavirin-free, pangenotypic, direct-acting antiviral regimen,
glecaprevir coformulated with pibrentasvir, has shown high rates of sustained virological …
glecaprevir coformulated with pibrentasvir, has shown high rates of sustained virological …
Hepatitis C virus resistance to direct-acting antiviral drugs in interferon-free regimens
JM Pawlotsky - Gastroenterology, 2016 - Elsevier
Treatment of hepatitis C virus (HCV) infection has progressed considerably with the
approval of interferon-free, direct-acting antiviral (DAA)-based combination therapies …
approval of interferon-free, direct-acting antiviral (DAA)-based combination therapies …
Outcomes after successful direct-acting antiviral therapy for patients with chronic hepatitis C and decompensated cirrhosis
Background & Aims Direct-acting antivirals have become widely used for patients with
chronic hepatitis C virus infection with decompensated cirrhosis. Virological responses are …
chronic hepatitis C virus infection with decompensated cirrhosis. Virological responses are …
Direct antiviral agent treatment of chronic hepatitis C results in rapid regression of transient elastography and fibrosis markers fibrosis‐4 score and aspartate …
JA Bachofner, PV Valli, A Kröger, I Bergamin… - Liver …, 2017 - Wiley Online Library
Background Novel direct antiviral agents (DAA) targeting hepatitis C virus (HCV) have
revolutionized the treatment of chronic hepatitis C infection (CHC). Rates of sustained …
revolutionized the treatment of chronic hepatitis C infection (CHC). Rates of sustained …
Global epidemiology, prevention, and management of hepatocellular carcinoma
LY Mak, V Cruz-Ramón, P Chinchilla-López… - American Society of …, 2018 - ascopubs.org
The incidence rate of hepatocellular carcinoma (HCC) is rising. It is one of the most common
cancers worldwide and accounts for substantial morbidity and mortality. Chronic hepatitis B …
cancers worldwide and accounts for substantial morbidity and mortality. Chronic hepatitis B …
Host-directed therapies for infectious diseases: current status, recent progress, and future prospects
Despite extensive global efforts in the fight against killer infectious diseases, they still cause
one in four deaths worldwide and are important causes of long-term functional disability …
one in four deaths worldwide and are important causes of long-term functional disability …