Vitamin D deficiency: consequence or cause of obesity?

L Vranić, I Mikolašević, S Milić - Medicina, 2019 - mdpi.com
Obesity is defined as an excess amount of body fat and represents a significant health
problem worldwide. High prevalence of vitamin D (VD) deficiency in obese subjects is a well …

Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases

LA Adams, QM Anstee, H Tilg, G Targher - Gut, 2017 - gut.bmj.com
Key physiological functions of the liver, including glucose and lipid metabolism, become
disturbed in the setting of non-alcoholic fatty liver disease (NAFLD) and may be associated …

Safety and efficacy of once-weekly efruxifermin versus placebo in non-alcoholic steatohepatitis (HARMONY): a multicentre, randomised, double-blind, placebo …

SA Harrison, JP Frias, G Neff, GA Abrams… - The Lancet …, 2023 - thelancet.com
Background Fibroblast growth factor 21 (FGF21) regulates metabolism and protects cells
against stress. Efruxifermin is a bivalent Fc–FGF21 analogue that replicates FGF21 agonism …

[HTML][HTML] Vitamin D and chronic diseases

H Wang, W Chen, D Li, X Yin, X Zhang, N Olsen… - Aging and …, 2017 - ncbi.nlm.nih.gov
Vitamin D is one of the essential nutrients to sustain the human health. As a member of the
steroid hormone family, it has a classic role in regulating metabolism of calcium and a non …

[HTML][HTML] Nonalcoholic fatty liver disease: a precursor of the metabolic syndrome

A Lonardo, S Ballestri, G Marchesini, P Angulo… - Digestive and Liver …, 2015 - Elsevier
The conventional paradigm of nonalcoholic fatty liver disease representing the “hepatic
manifestation of the metabolic syndrome” is outdated. We identified and summarized …

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

QM Anstee, G Targher, CP Day - Nature reviews Gastroenterology & …, 2013 - nature.com
NAFLD is a spectrum of progressive liver disease that encompasses simple steatosis,
NASH, fibrosis and, ultimately, cirrhosis. NAFLD is recognized as the hepatic component of …

The role of vitamin D and vitamin D binding protein in chronic liver diseases

TL Pop, C Sîrbe, G Benţa, A Mititelu… - International journal of …, 2022 - mdpi.com
Vitamin D (calciferol) is a fat-soluble vitamin that has a significant role in phospho-calcium
metabolism, maintaining normal calcium levels and bone health development. The most …

Oxidative stress as a critical factor in nonalcoholic fatty liver disease pathogenesis

S Spahis, E Delvin, JM Borys, E Levy - Antioxidants & redox …, 2017 - liebertpub.com
Significance: Nonalcoholic fatty liver disease (NAFLD), characterized by liver triacylglycerol
build-up, has been growing in the global world in concert with the raised prevalence of …

Vitamin D and metabolic dysfunction-associated fatty liver disease (MAFLD): an update

I Barchetta, FA Cimini, MG Cavallo - Nutrients, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the first cause of chronic liver disease
worldwide; it ranges from simple steatosis to steatohepatitis (NASH) and, potentially …

Dietary supplementation of bile acid attenuate adverse effects of high-fat diet on growth performance, antioxidant ability, lipid accumulation and intestinal health in …

P Yin, S Xie, Z Zhuang, X He, X Tang, L Tian, Y Liu… - Aquaculture, 2021 - Elsevier
Bile acid (BA) has been reported to improve growth performance and play an important role
in lipid metabolism of fish. Five diets were formulated to investigate the effects of dietary bile …