Proteases are a set of enzymes that have been involved in multiple biological processes
throughout evolution. Among them, extracellular matrix (ECM) remodeling has emerged as …

The collagen network is altered in fibrotic diseases associated with extracellular matrix
(ECM) biosynthesis and remodeling. This mini-review focuses on the quantitative and …

Accurate prediction of peritoneal metastasis for gastric cancer (GC) with serosal invasion is
crucial in clinic. The presence of collagen in the tumour microenvironment affects the …

Background and aim: Collagen fibers are the main component of atherosclerotic lesions and
should therefore be used as an index to evaluate plaque stability. Although Masson's …

The ability to respond to injury with tissue repair is a fundamental property of all multicellular
organisms. The extracellular matrix (ECM), composed of fibrillar collagens as well as a …

Multiphoton microscopy has recently passed the milestone of its first 30 years of activity in
biomedical research. The growing interest around this approach has led to a variety of …

Biological tissues are not uniquely composed of cells. A substantial part of their volume is
extracellular space, which is primarily filled by an intricate network of macromolecules …

Macrophages (Mφs) produce factors that participate in cardiac repair and remodeling after
myocardial infarction (MI); however, how these factors crosstalk with other cell types …

Current liver fibrosis scoring by computer-assisted image analytics is not fully automated as
it requires manual preprocessing (segmentation and feature extraction) typically based on …

Texture analysis describes a variety of image analysis techniques that quantify the variation
in intensity and pattern. This paper provides an overview of several texture analysis …