Background Neurotropic B vitamins play crucial roles as coenzymes and beyond in the
nervous system. Particularly vitamin B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) …

Abstract Thiamine (thiamin, B1) is a vitamin necessary for proper cell function. It exists in a
free form as a thiamine, or as a mono-, di-or triphosphate. Thiamine plays a special role in …

Obesity and diabetes are increasing in prevalence worldwide. Despite excessive dietary
consumption, obese individuals have high rates of micronutrient deficiencies. Deficiencies of …

Nutritional management of blood glucose levels is a strategic target in the prevention and
management of type 2 diabetes mellitus (T2DM). To implement such an approach, it is …

Micronutrients influence hormone action and host metabolism. Dietary minerals, trace
elements, and vitamins can alter blood glucose and cellular glucose metabolism, and …

Thiamine is a water-soluble vitamin that plays an important role in the energy metabolism in
the human body. Deficiency in thiamine can lead to neurological abnormalities and …

Thiamine or vitamin B1 is an essential, water-soluble vitamin required for mitochondrial
energetics—the production of adenosine triphosphate (ATP). It is a critical and rate-limiting …

Background Thiamine (vitamin B1) is an essential cofactor in glucose metabolism, but it
remains unclear whether thiamine status is lower in individuals with diabetes compared to …

Type 2 diabetes is characterized by significant losses of important micronutrients due to
metabolic basis of the disease and its complications. Evidence of changes in trace mineral …

Thiamine (vitamin B1) is a precursor of the well-known coenzyme of central metabolic
pathways thiamine diphosphate (ThDP). Highly intense glucose oxidation in the brain …