Nanoparticle protein corona: from structure and function to therapeutic targeting

G Bashiri, MS Padilla, KL Swingle, SJ Shepherd… - Lab on a Chip, 2023 - pubs.rsc.org
Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …

Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli‐responsive, toxicity, immunogenicity, and clinical translation

E Sharifi, A Bigham, S Yousefiasl, M Trovato… - Advanced …, 2022 - Wiley Online Library
Cancer is one of the top life‐threatening dangers to the human survival, accounting for over
10 million deaths per year. Bioactive glasses have developed dramatically since their …

Rapid SARS-CoV-2 spike protein detection by carbon nanotube-based near-infrared nanosensors

RL Pinals, F Ledesma, D Yang, N Navarro, S Jeong… - Nano Letters, 2021 - ACS Publications
To effectively track and eliminate COVID-19, it is critical to develop tools for rapid and
accessible diagnosis of actively infected individuals. Here, we introduce a single-walled …

Nanomaterials in anticancer applications and their mechanism of action-A review

CGA Das, VG Kumar, TS Dhas, V Karthick… - … , Biology and Medicine, 2023 - Elsevier
The current challenges in cancer treatment using conventional therapies have made the
emergence of nanotechnology with more advancements. The exponential growth of …

How nanoparticles open the paracellular route of biological barriers: mechanisms, applications, and prospects

J Wu, Z Zhu, W Liu, Y Zhang, Y Kang, J Liu, C Hu… - ACS …, 2022 - ACS Publications
Biological barriers are essential physiological protective systems and obstacles to drug
delivery. Nanoparticles (NPs) can access the paracellular route of biological barriers, either …

The role of protein corona on nanodrugs for organ-targeting and its prospects of application

S Wang, J Zhang, H Zhou, YC Lu, X Jin, L Luo… - Journal of Controlled …, 2023 - Elsevier
Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …

Artificial engineering of the protein corona at bio-nano interfaces for improved cancer-targeted nanotherapy

S Khan, M Sharifi, JP Gleghorn, MMN Babadaei… - Journal of Controlled …, 2022 - Elsevier
Nanoparticles (NPs) have been used in numerous applications as anticancer, antibacterial
and antioxidant agents. Artificial engineering of protein interactions with NPs in biological …

The Janus of Protein Corona on nanoparticles for tumor targeting, immunotherapy and diagnosis

X Wang, W Zhang - Journal of Controlled Release, 2022 - Elsevier
The therapeutics based on nanoparticles (NPs) are considered as the promising strategy for
tumor detection and treatment. However, one of the most challenges is the adsorption of …

Biological features of nanoparticles: protein corona formation and interaction with the immune system

S Panico, S Capolla, S Bozzer, G Toffoli, M Dal Bo… - Pharmaceutics, 2022 - mdpi.com
Nanoparticles (NPs) are versatile candidates for nanomedical applications due to their
unique physicochemical properties. However, their clinical applicability is hindered by their …

Unifying structural descriptors for biological and bioinspired nanoscale complexes

M Cha, EST Emre, X Xiao, JY Kim, P Bogdan… - Nature Computational …, 2022 - nature.com
Biomimetic nanoparticles are known to serve as nanoscale adjuvants, enzyme mimics and
amyloid fibrillation inhibitors. Their further development requires better understanding of …