Neurological disorders significantly outnumber diseases in other therapeutic areas.
However, developing drugs for central nervous system (CNS) disorders remains the most …

Functional ultrasound (fUS) is a neuroimaging method that uses ultrasound to track changes
in cerebral blood volume as an indirect readout of neuronal activity at high spatiotemporal …

Methods for noninvasive brain imaging are highly desirable to study brain structures in
neuroscience. Two‐photon fluorescence microscopy (2PFM) with near‐infrared (NIR) light …

The term neurovascular unit (NVU) describes the structural and functional liaison between
specialized brain endothelium, glial and mural cells, and neurons. Within the NVU, the blood …

Cancer is still the leading disease threatening human life and health at present. With the
development of nanotechnology, multifunctional nanomaterials integrated with different …

Imaging based on blood flow dynamics is widely used to study sensory processing. Here we
investigated the extent to which local neuronal and capillary responses (two-photon …

Fluorogens with aggregation-induced emission (AIEgens) are promising optical agents for
cellular and vascular imaging. AIEgens with bright emission in the far-red and near-infrared …

Aggregation induced emission (AIE)-active bright two-photon fluorescent probes with
second near-infrared (NIR-II) light excitability can be used for efficient brain bioimaging …

Imaging large-scale circuit dynamics is crucial to understanding brain function, but most
techniques have a limited depth of field. Here, we describe volumetric functional ultrasound …

Two‐photon fluorescence imaging allows in vivo study of biological structures and activities
in deep tissues, in which bright fluorophores with high photostability and good …