ERK mediates interferon gamma-induced melanoma cell death
A Champhekar, R Heymans, J Saco, G Turon Font… - Molecular Cancer, 2023 - Springer
Background Interferon-gamma (IFNγ) exerts potent growth inhibitory effects on a wide range
of cancer cells through unknown signaling pathways. We pursued complementary screening …
of cancer cells through unknown signaling pathways. We pursued complementary screening …
Revisiting the chaperonin T‐complex protein‐1 ring complex in human health and disease: A proteostasis modulator and beyond
C Zeng, S Han, Y Pan, Z Huang… - Clinical and …, 2024 - Wiley Online Library
Background Disrupted protein homeostasis (proteostasis) has been demonstrated to
facilitate the progression of various diseases. The cytosolic T‐complex protein‐1 ring …
facilitate the progression of various diseases. The cytosolic T‐complex protein‐1 ring …
PD-L1 and IFN-γ modulate Non-Small Cell Lung Cancer (NSCLC) cell plasticity associated to immune checkpoint inhibitor (ICI)-mediated hyperprogressive disease …
S Angelicola, F Giunchi, F Ruzzi, M Frascino… - Journal of Translational …, 2025 - Springer
Abstract Background Non-Small Cell Lung Cancer (NSCLC) is the leading cause of cancer
death worldwide. Although immune checkpoint inhibitors (ICIs) have shown remarkable …
death worldwide. Although immune checkpoint inhibitors (ICIs) have shown remarkable …
Development and experimental validation of a folate metabolism-related gene signature to predict the prognosis and immunotherapeutic sensitivity in bladder cancer
X Liu, C Chen, P Xu, B Chen, A Xu, C Liu - Functional & Integrative …, 2023 - Springer
Folate metabolism is critical for the maintenance of genomic stability due to its regulatory
ability to methylation, nucleotide metabolism, and reduction capabilities in cancer cells …
ability to methylation, nucleotide metabolism, and reduction capabilities in cancer cells …