Aedes Mosquito Salivary Components and Their Effect on the Immune Response to Arboviruses

D Guerrero, T Cantaert, D Missé - Frontiers in cellular and infection …, 2020 - frontiersin.org
Vector-borne diseases are responsible for over a billion infections each year and nearly one
million deaths. Mosquito-borne dengue virus, West Nile, Japanese encephalitis, Zika …

Intrinsic factors driving mosquito vector competence and viral evolution: a review

J Lewis, EN Gallichotte, J Randall, A Glass… - Frontiers in Cellular …, 2023 - frontiersin.org
Mosquitoes are responsible for the transmission of numerous viruses of global health
significance. The term “vector competence” describes the intrinsic ability of an arthropod …

In silico design of a multi-epitope Chimera from Aedes aegypti salivary proteins OBP 22 and OBP 10: A promising candidate vaccine

S Sankar - Journal of Vector Borne Diseases, 2022 - journals.lww.com
Methods: Linear and conformation B-cell epitopes and MHC class-I and class-II binding T-
cell epitopes were predicted using bioinformatic tools. Selected B-and T-cell epitopes were …

High resolution proteomics of Aedes aegypti salivary glands infected with either dengue, Zika or chikungunya viruses identify new virus specific and broad antiviral …

A Chowdhury, CM Modahl, D Missé, RM Kini… - Scientific Reports, 2021 - nature.com
Arboviruses such as dengue (DENV), Zika (ZIKV) and chikungunya (CHIKV) viruses infect
close to half a billion people per year, and are primarily transmitted through Aedes aegypti …

Anopheles salivary antigens as serological biomarkers of vector exposure and malaria transmission: A systematic review with multilevel modelling

EA Kearney, PA Agius, V Chaumeau, JC Cutts… - Elife, 2021 - elifesciences.org
Background: Entomological surveillance for malaria is inherently resource-intensive and
produces crude population-level measures of vector exposure which are insensitive in low …

Aedes–Chikungunya Virus Interaction: Key Role of Vector Midguts Microbiota and Its Saliva in the Host Infection

VVS Monteiro, KC Navegantes-Lima… - Frontiers in …, 2019 - frontiersin.org
Aedes mosquitoes are important vectors for emerging diseases caused by arboviruses, such
as chikungunya (CHIKV). These viruses' main transmitting species are Aedes aegypti and …

Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail

J Wang, EJ Murphy, JC Nix, DNM Jones - Scientific Reports, 2020 - nature.com
Aedes aegypti is the primary vector for transmission of Dengue, Zika and chikungunya
viruses. Previously it was shown that Dengue virus infection of the mosquito led to an in …

The regulatory genome of the malaria vector Anopheles gambiae: integrating chromatin accessibility and gene expression

JL Ruiz, LC Ranford-Cartwright… - NAR genomics and …, 2021 - academic.oup.com
Anopheles gambiae mosquitoes are primary human malaria vectors, but we know very little
about their mechanisms of transcriptional regulation. We profiled chromatin accessibility by …

Research progress toward the influence of mosquito salivary proteins on the transmission of mosquito‐borne viruses

ZY Wang, KX Nie, JC Niu, G Cheng - Insect Science, 2024 - Wiley Online Library
Mosquito‐borne viruses (MBVs) are a large class of viruses transmitted mainly through
mosquito bites, including dengue virus, Zika virus, Japanese encephalitis virus, West Nile …

Mosquito saliva reshapes alphavirus infection and immunopathogenesis

SW Fong, RM Kini, LFP Ng - Journal of virology, 2018 - Am Soc Microbiol
Alphaviruses are transmitted to humans via bites of infected mosquitoes. Although
alphaviruses have caused a wide range of outbreaks and crippling disease, the availability …