Circulating markers of oxidative stress and polycystic ovary syndrome (PCOS): a systematic review and meta-analysis

M Murri, M Luque-Ramírez, M Insenser… - Human reproduction …, 2013 - academic.oup.com
BACKGROUND Oxidative stress might be associated with polycystic ovary syndrome
(PCOS), but relatively small studies published to date do not permit reaching a definitive …

Ascorbic acid: its role in immune system and chronic inflammation diseases

A Sorice, E Guerriero, F Capone… - Mini reviews in …, 2014 - ingentaconnect.com
Ascorbic acid (AA), also known as vitamin C, was initially identified as the factor preventing
the scurvy disease, and became very popular for its antioxidant properties. It is an important …

Antioxidant-rich natural fruit and vegetable products and human health

AIO Jideani, H Silungwe, T Takalani… - … Journal of Food …, 2021 - Taylor & Francis
Antioxidants are important ingredients that are present in fruits and vegetables (FAV). With
increased consumption of FAV in its raw and processed form, a predominantly plant-based …

Vitamin C supplementation for diabetes management: A comprehensive narrative review

SA Mason, L Parker, P van der Pligt… - Free Radical Biology and …, 2023 - Elsevier
Growing evidence suggests that vitamin C supplementation may be an effective adjunct
therapy in the management of people with diabetes. This paper critically reviews the current …

The unfolded protein response: a pathway that links insulin demand with β-cell failure and diabetes

D Scheuner, RJ Kaufman - Endocrine reviews, 2008 - academic.oup.com
The endoplasmic reticulum (ER) is the entry site into the secretory pathway for newly
synthesized proteins destined for the cell surface or released into the extracellular milieu …

Vitamin C in the treatment and/or prevention of obesity

DF Garcia-Diaz, P Lopez-Legarrea… - Journal of nutritional …, 2014 - jstage.jst.go.jp
Obesity has emerged as one of the major health threats worldwide. Moreover, an excessive
body fat accumulation, which defines this disease, could lead to several associated clinical …

[HTML][HTML] Redox balance in type 2 diabetes: therapeutic potential and the challenge of antioxidant-based therapy

L Argaev-Frenkel, T Rosenzweig - Antioxidants, 2023 - mdpi.com
Oxidative stress is an important factor in the development of type 2 diabetes (T2D) and
associated complications. Unfortunately, most clinical studies have failed to provide …

[HTML][HTML] Research Progress on the Relationship between Vitamins and Diabetes: Systematic Review

J Liu, L Qin, J Zheng, L Tong, W Lu, C Lu, J Sun… - International Journal of …, 2023 - mdpi.com
Diabetes is a serious chronic metabolic disease that causes complications over time,
bringing serious public health challenges that affect different countries across the world. The …

Ascorbic acid inhibits visceral obesity and nonalcoholic fatty liver disease by activating peroxisome proliferator-activated receptor α in high-fat-diet-fed C57BL/6J mice

H Lee, J Ahn, SS Shin, M Yoon - International journal of obesity, 2019 - nature.com
Background/objectives: Ascorbic acid is a known cofactor in the biosynthesis of carnitine, a
molecule that has an obligatory role in fatty acid oxidation. Our previous studies have …

Lipoic acid improves mitochondrial function in nonalcoholic steatosis through the stimulation of sirtuin 1 and sirtuin 3

MP Valdecantos, P Pérez‐Matute… - …, 2012 - Wiley Online Library
Nonalcoholic steatosis is an important hepatic complication of obesity linked to
mitochondrial dysfunction and oxidative stress. Lipoic acid (LA) has been reported to have …