Identifying repeating motifs in the activation of synchronized bursts in cultured neuronal networks

N Raichman, E Ben-Jacob - Journal of neuroscience methods, 2008 - Elsevier
Cultured neuronal networks cultivated on micro-electrode arrays are a widely used tool for
the investigation of network mechanisms, providing structural framework for long-term …

Effects of random external background stimulation on network synaptic stability after tetanization: a modeling study

ZC Chao, DJ Bakkum, DA Wagenaar, SM Potter - Neuroinformatics, 2005 - Springer
We constructed a simulated spiking neural network model to investigate the effects of
random background stimulation on the dynamics of network activity patterns and tetanus …

Analysis of cultured neuronal networks using intraburst firing characteristics

J Stegenga, J Le Feber, E Marani… - IEEE transactions on …, 2008 - ieeexplore.ieee.org
It is an open question whether neuronal networks, cultured on multielectrode arrays, retain
any capability to usefully process information (learning and memory). A necessary …

Transient epileptiform signaling during neuronal network development: regulation by external stimulation and bimodal GABAergic activity

JM Zemianek, AM Shultz, S Lee, M Guaraldi… - International Journal of …, 2013 - Elsevier
A predominance of excitatory activity, with protracted appearance of inhibitory activity,
accompanies cortical neuronal development. It is unclear whether or not inhibitory neuronal …

Accelerated establishment of mature signaling patterns following stimulation of developing neuronal networks:“learning” versus “plasticity”

JM Zemianek, S Lee, M Guaraldi, TB Shea - International journal of …, 2012 - Elsevier
Neuronal networks established on micro-electrode arrays provide useful models for synaptic
plasticity. Whether or not this represents a facet of learning is debated since ex vivo …

Interactive sonification: Aesthetics, functionality and performance

G Weinberg, T Thatcher - Leonardo Music Journal, 2006 - direct.mit.edu
The authors present a sonification installation that allows a group of players to interact with
an auditory display of neural activity. The system is designed to represent electrical spike …

Critical role for inhibitory neurons in modulation of synaptic signaling in ex vivo neuronal networks

JM Zemianek, S Lee, M Guaraldi, TB Shea - International Journal of …, 2013 - Elsevier
A number of laboratories have modeled aspects of synaptic plasticity using neuronal
networks established on micro-electrode arrays. Such studies demonstrate that external …

[HTML][HTML] Robot-embodied neuronal networks as an interactive model of learning

AM Shultz, S Lee, M Guaraldi, TB Shea… - The Open Neurology …, 2017 - ncbi.nlm.nih.gov
Method: This article describes the embodiment of ex vivo neuronal networks neurons in a
closed-loop cybernetic system, consisting of digitized video signals as sensory input and a …

Neuron-on-a-chip technology: Microelectrode array system and neuronal patterning

YK Nam - Journal of Biomedical Engineering Research, 2009 - koreascience.kr
Neuron-on-a-Chip technology is based on advanced neuronal culture technique, surface
micropatterning, microelectrode array technology, and multi-dimensional data analysis …

Synaptic signal streams generated by ex vivo neuronal networks contain non-random, complex patterns

S Lee, JM Zemianek, A Shultz, A Vo, BY Maron… - International Journal of …, 2014 - Elsevier
Cultured embryonic neurons develop functional networks that transmit synaptic signals over
multiple sequentially connected neurons as revealed by multi-electrode arrays (MEAs) …