Targeting sphingolipids for cancer therapy

O Companioni, C Mir, Y Garcia-Mayea… - Frontiers in …, 2021 - frontiersin.org
Sphingolipids are an extensive class of lipids with different functions in the cell, ranging from
proliferation to cell death. Sphingolipids are modified in multiple cancers and are …

[HTML][HTML] Chronic inflammation, neuroglial dysfunction, and plasmalogen deficiency as a new pathobiological hypothesis addressing the overlap between post-COVID …

AM Chaves-Filho, O Braniff, A Angelova, Y Deng… - Brain Research …, 2023 - Elsevier
After five waves of coronavirus disease 2019 (COVID-19) outbreaks, it has been recognized
that a significant portion of the affected individuals developed long-term debilitating …

Production and Characterization of Exopolysaccharide From Newly Isolated Marine Probiotic Lactiplantibacillus plantarum EI6 With in vitro Wound Healing Activity

EH Zaghloul, MIA Ibrahim - Frontiers in Microbiology, 2022 - frontiersin.org
Because of its safety, biological activities, and unique properties, exopolysaccharide (EPS)
from lactic acid bacteria (LAB) has been developed as a potential biopolymer. A few studies …

Antiviral, Cytotoxic, and Antioxidant Activities of Three Edible Agaricomycetes Mushrooms: Pleurotus columbinus, Pleurotus sajor-caju, and Agaricus bisporus

SM Elhusseiny, TS El-Mahdy, MF Awad, NS Elleboudy… - Journal of Fungi, 2021 - mdpi.com
In this study, we investigated aqueous extracts of three edible mushrooms: Agaricus
bisporus (white button mushroom), Pleurotus columbinus (oyster mushroom), and Pleurotus …

Histological assessment, anti-quorum sensing, and anti-biofilm activities of Dioon spinulosum extract: in vitro and in vivo approach

E Elekhnawy, WA Negm, M El-Aasr, AA Kamer… - Scientific reports, 2022 - nature.com
Pseudomonas aeruginosa is an opportunistic bacterium causing several health problems
and having many virulence factors like biofilm formation on different surfaces. There is a …

Proteome Analysis and In Vitro Antiviral, Anticancer and Antioxidant Capacities of the Aqueous Extracts of Lentinula edodes and Pleurotus ostreatus Edible …

SM Elhusseiny, TS El-Mahdy, MF Awad, NS Elleboudy… - Molecules, 2021 - mdpi.com
In this study, we examined aqueous extracts of the edible mushrooms Pleurotus ostreatus
(oyster mushroom) and Lentinula edodes (shiitake mushroom). Proteome analysis was …

Enhanced in vivo wound healing efficacy of a novel hydrogel loaded with copper (II) Schiff base quinoline complex (CuSQ) solid lipid nanoparticles

D Abou El-ezz, LH Abdel-Rahman, BS Al-Farhan… - Pharmaceuticals, 2022 - mdpi.com
Wound dressings created using nanotechnology are known as suitable substrates to speed
up the healing of both acute and chronic wounds. Therapeutic substances can be delivered …

Promising targets of chrysin and daidzein in colorectal cancer: Amphiregulin, CXCL1, and MMP-9

AAA Salama, RM Allam - European journal of pharmacology, 2021 - Elsevier
Colorectal cancer is one of the primary causes of cancer-related mortality worldwide. The
tumor microenvironment contains growth factors; inflammatory chemokines, matrix …

Synthesis, characterization, and cytotoxicity of self-assembly of hybrid nanocomposite modified membrane of carboxymethyl cellulose/graphene oxide for …

NM El-Shafai, MM Ibrahim, M Abdelfatah… - Colloids and Surfaces A …, 2021 - Elsevier
In this work, carboxymethylcellulose (CMC) macrostructure has been incorporated with
graphene oxide nanosheet (GO) to form a hybrid composite as a modified surface for …

TPGS surface modified bilosomes as boosting cytotoxic oral delivery systems of curcumin against doxorubicin resistant MCF-7 breast cancer cells

H Hegazy, MM Amin, W Fayad, MY Zakaria - International Journal of …, 2022 - Elsevier
The goal of this work was to design nude bilosomes (Bil) and D-alpha-tocopheryl
polyethylene glycol succinate (TPGS) surface coated bilosomes as an oral delivery platform …