Neuroinflammation has been identified as a causative factor of multiple neurological
diseases. The nucleotide-binding oligomerization domain-, leucine-rich repeat-and pyrin …

Neurons are usually regarded as postmitotic cells that undergo apoptosis in response to cell
cycle reactivation. Nevertheless, recent evidence indicates the existence of a defined …

Traumatic brain injury (TBI) induces secondary biochemical changes that contribute to
delayed neuroinflammation, neuronal cell death, and neurological dysfunction. Attenuating …

Massive neuronal loss is a key pathological hallmark of Alzheimer's disease (AD). However,
the mechanisms are still unclear. Here we demonstrate that neuroinflammation, cell …

The cell cycle is a delicately manipulated process essential for the development,
differentiation, proliferation and death of cells. Inappropriate activation of cell cycle …

Cognitive dysfunction has been reported in patients with spinal cord injury (SCI), but it has
been questioned whether such changes may reflect concurrent head injury, and the issue …

Primary and secondary traumatic brain injury (TBI) can cause tissue damage by inducing
cell death pathways including apoptosis, necroptosis, and autophagy. However, similar …

Neuroprosthetic devices have made a major impact in the treatment of a variety of disorders
such as paralysis and stroke. However, a major impediment in the advancement of this …

Neuropathic pain after spinal cord injury (SCI) is common, often intractable, and can be
severely debilitating. A number of mechanisms have been proposed for this pain, which are …

The DNA damage response is a key factor in the maintenance of genome stability. As such,
it is a central axis in sustaining cellular homeostasis in a variety of contexts: development …