Abstract Turner syndrome affects 25–50 per 100,000 females and can involve multiple
organs through all stages of life, necessitating multidisciplinary approach to care. Previous …

Children born small for gestational age (SGA), defined as a birth weight and/or length
below− 2 SD score (SDS), comprise a heterogeneous group. The causes of SGA are …

Objective: Our objective was to summarize important advances in the management of
children with idiopathic short stature (ISS). Participants: Participants were 32 invited leaders …

Objective: Our objective was to formulate practice guidelines for the treatment and
prevention of pediatric obesity. Conclusions: We recommend defining overweight as body …

SHOX deficiency is a frequent cause of short stature. The short stature homeobox-containing
gene resides in the telomeric PAR1 region on the short arm of both sex chromosomes and …

Context: Genetics plays a major role in determining an individual's height. Although there
are many monogenic disorders that lead to perturbations in growth and result in short …

The pseudoautosomal regions (PAR1 and PAR2) of the human X and Y chromosomes pair
and recombine during meiosis. Thus genes in this region are not inherited in a strictly sex …

Idiopathic short stature is a condition in which the height of the individual is more than 2 SD
below the corresponding mean height for a given age, sex and population, in whom no …

SHOX deficiency is the most frequent genetic growth disorder associated with isolated and
syndromic forms of short stature. Caused by mutations in the homeobox gene SHOX, its …

For early detection of pathological causes of growth failure proper referral criteria are
needed, as well as a thorough clinical, radiological and laboratory assessment. In this …