A review on sources and pharmacological aspects of sakuranetin

M Stompor - Nutrients, 2020 - mdpi.com
Sakuranetin belongs to the group of methoxylated flavanones. It is widely distributed in
Polyomnia fruticosa and rice, where it acts as a phytoalexin. Other natural sources of this …

The Role and Mechanism of Perilla frutescens in Cancer Treatment

S Huang, Y Nan, G Chen, N Ning, Y Du, D Lu, Y Yang… - Molecules, 2023 - mdpi.com
Perilla frutescens is an annual herb of the Labiatae family and is widely grown in several
countries in Asia. Perilla frutescens is a plant that is used medicinally in its entirety, as seen …

Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer

EA Abdelsalam, AA Abd El-Hafeez… - Journal of enzyme …, 2022 - Taylor & Francis
New series of thiazolyl-pyrazoline derivatives (7a–7d, 10a–10d and 13a–13f) have been
synthesised and assessed for their potential EGFR and VEGFR-2 inhibitory activities …

Dietary natural products and lung cancer: Effects and mechanisms of action

SY Cao, Y Li, X Meng, CN Zhao, S Li, RY Gan… - Journal of functional …, 2019 - Elsevier
Lung cancer is the most common cancer and the leading cause of cancer-related death
worldwide. Increasing evidence suggests an important role of dietary natural products in the …

Anti-cancer Effect of Hyoscyamus muticus Extract via Its Activation of Fas/FasL-ASK1-p38 Pathway

AA Abd El-Hafeez, HMM Marzouk… - Biotechnology and …, 2022 - Springer
Hyoscyamus muticus L. is a traditional medicine used as antispasmodic and sedative.
Herein, we aimed to determine the phytochemical constituents and for the first time its anti …

Establishment and characterization of a radiation‐induced dermatitis rat model

X Sheng, Y Zhou, H Wang, Y Shen… - Journal of Cellular …, 2019 - Wiley Online Library
Radiation‐induced dermatitis is a common and serious side effect after radiotherapy.
Current clinical treatments cannot efficiently or fully prevent the occurrence of post …

Melilotus indicus extract induces apoptosis in hepatocellular carcinoma cells via a mechanism involving mitochondria-mediated pathways

AA Abd El-Hafeez, HO Khalifa, RA Elgawish… - Cytotechnology, 2018 - Springer
Melilotus indicus, is a traditional medicine used as analgesic and emollient. Although
Melilotus indicus extract (MIE) has recently been shown to suppress growth of several tumor …

A Methoxyflavanone from Perilla frutescens Induces Cellular Senescence in A549 Human Lung Adenocarcinoma Cells but Not in Normal Human Bronchial Epithelial …

A Maeda, T Fujimura, N Hirakawa, K Baba… - Biological and …, 2022 - jstage.jst.go.jp
Cellular senescence is an inherent tumor suppressive process, and cancer-targeted
senescence induction represents an attractive anti-tumor strategy. Here, we show that a …

[HTML][HTML] Correlation of ARNTL2 with immune infiltration and its role as a potential prognostic biomarker in lung adenocarcinoma

J Pan, H Yang, L Zhu, Y Lou - Clinical Complementary Medicine and …, 2021 - Elsevier
Background ARNTL2 is a core component of the circadian clock genes and plays regulatory
roles in the cell cycle and immune infiltration, but its mechanism in lung cancer (LC) remains …

A methoxyflavanone from the medicinal herb Perilla frutescens down-modulates Th17 response and ameliorates collagen-induced arthritis

A Maeda, K Hirano, S Maeda, A Okuizumi… - Biochemical and …, 2022 - Elsevier
Abstract IL-17-producing T-helper 17 (Th17) cells are involved in the pathogenesis of
autoimmune disorders such as rheumatoid arthritis (RA). Here, we show that a …