Currently available data on the involvement of neuropeptide Y (NPY), peptide YY (PYY), and
pancreatic polypeptide (PP) and their receptors (YRs) in cancer are updated. The structure …

The tumor microenvironment (TME) plays an essential role in the development and
progression of neoplasms. TME consists of the extracellular matrix and numerous …

Background Cancer stroma contains the neural compartment with specific components and
action. Neural microenvironment processing includes among others axonogenesis …

Abstract Purpose Neuropeptide Y (NPY) is a pleiotropic peptide, which is involved in many
biological mechanisms important in regulation of cell growth and survival. The aim of this …

Docetaxel (DTX) was the first chemotherapeutic agent to demonstrate significant efficacy in
the treatment of men with metastatic castration-resistant prostate cancer. However, response …

miR-615-3p has previously been described as up-regulated in prostate cancer (PC) tissue
samples compared with nonmalignant controls; however, its prognostic potential and …

Background Tumor microenvironment and its interaction with neuroendocrine modulators
contribute to prostate carcinogenesis and progression. Objective We sought to define the …

Improved prostate cancer prognostic biomarkers are urgently needed. We previously
identified the four-miRNA prognostic biomarker panel MiCaP ((miR-23a-3p× miR-10b …

Aims Zinc-alpha 2-glycoprotein (AZGP1) is a promising tissue biomarker to predict outcomes
in men undergoing treatment for localised prostate cancer (PCa). We aimed to examine the …

This study aimed to validate whether 5-hydroxymethylcytosine (5hmC) level in combination
with ERG expression is a predictive biomarker for biochemical failure (BF) in men …