From a neurobiological perspective there is no such thing as bipolar disorder. Rather, it is
almost certainly the case that many somewhat similar, but subtly different, pathological …

Bipolar disorder (BP) is a chronic neuropsychiatric condition characterized by pathological
fluctuations in mood from mania to depression. Adoption, twin and family studies have …

Inhibitory interneurons are crucial to brain function and their dysfunction is implicated in
neuropsychiatric conditions. Emerging evidence indicates that cholecystokinin (CCK) …

Schizophrenia is a highly debilitating mental disorder which afflicts approximately 1% of the
global population. Cognitive and negative deficits account for the lifelong disability …

With the continuing development and improvement of genome-wide techniques, a great
number of candidate genes are discovered. How to identify the most likely disease genes …

The vast majority of proteins that are transported to different cellular compartments and
secreted from the cell require coat protein complex II (COPII) for export from the endoplasmic …

Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric conditions with a
neurodevelopmental component. Genetic findings indicate the existence of an overlap in …

Background The involvement of multiple genes and missing heritability, which are dominant
in complex diseases such as multiple sclerosis (MS), entail using network biology to better …

Background Parkinson's Disease (PD) is one of the most prevailing neurodegenerative
diseases. Improving diagnoses and treatments of this disease is essential, as currently there …

Objective To provide a strategic framework for the prevention of bipolar disorder (BD) that
incorporates a 'Big Data'approach to risk assessment for BD. Methods Computerized …