Gamma‐glutamyltransferase (GGT) is a well‐established serum marker for alcohol‐related
liver disease. However, GGT's predictive utility applies well beyond liver disease: elevated …

Endocrine complications due to haemosiderosis are present in a significant number of
patients with beta‐thalassemia major (BTM) worldwide and often become barriers in their …

We previously demonstrated that iron overload induces liver damage by causing the
formation of reactive oxygen species (ROS). Taurine is a potent free radical scavenger that …

Background: Thalassemia is one of the most common hereditary disorders and Beta-
thalassemia major is its severe form. The present study is concerned with the analysis of …

Major β‐thalassemia (β‐TM) is one of the most common inherited hemolytic types of anemia
which is caused as a result of absent or reduced synthesis of β‐globin chains of …

Abstract β-Thalassemia (β-thal) is a genetic disorder, representing a major health problem in
Algeria. It is associated with altered lipid levels and a state of oxidative stress that can lead …

The impaired biosynthesis of the β-globin chain in β-thalassemia leads to the accumulation
of unpaired alpha globin chains, failure in hemoglobin formation, and iron overload due to …

Thalassemia is a genetic disease caused by disruption of globin chain synthesis leading to
severe anemia and thus regular blood transfusion is necessary. However, there have been …

Abstract Background: Endothelin-1 (ET-1), a potent endogenous vasoconstrictor, stimulates
production of reactive oxygen species. Endothelial monocyte-activating polypeptide-II …

ABSTRACT Introduction: Silibinin (silybin), a non-toxic natural polyphenolic flavonoid, is the
principal and the most biologically active component of silymarin. It is efficient in the …