Advances in nanomaterial vaccine strategies to address infectious diseases impacting global health

CN Fries, EJ Curvino, JL Chen, SR Permar… - Nature …, 2021 - nature.com
Despite the overwhelming success of vaccines in preventing infectious diseases, there
remain numerous globally devastating diseases without fully protective vaccines, particularly …

Nanoparticle vaccines against infectious diseases

R Pati, M Shevtsov, A Sonawane - Frontiers in immunology, 2018 - frontiersin.org
Due to emergence of new variants of pathogenic micro-organisms the treatment and
immunization of infectious diseases have become a great challenge in the past few years. In …

Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Cell membrane-derived nanomaterials for biomedical applications

RH Fang, Y Jiang, JC Fang, L Zhang - Biomaterials, 2017 - Elsevier
The continued evolution of biomedical nanotechnology has enabled clinicians to better
detect, prevent, manage, and treat human disease. In order to further push the limits of …

Applications of nanotechnology for immunology

DM Smith, JK Simon, JR Baker Jr - Nature Reviews Immunology, 2013 - nature.com
Nanotechnology uses the unique properties of objects that function as a unit within the
overall size range of 1–1,000 nanometres. The engineering of nanostructure materials …

Recent advances in self-assembled peptides: Implications for targeted drug delivery and vaccine engineering

S Eskandari, T Guerin, I Toth, RJ Stephenson - Advanced drug delivery …, 2017 - Elsevier
Self-assembled peptides have shown outstanding characteristics for vaccine delivery and
drug targeting. Peptide molecules can be rationally designed to self-assemble into specific …

[HTML][HTML] Self-assembling protein nanoparticles in the design of vaccines

J López-Sagaseta, E Malito, R Rappuoli… - Computational and …, 2016 - Elsevier
For over 100 years, vaccines have been one of the most effective medical interventions for
reducing infectious disease, and are estimated to save millions of lives globally each year …

Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development

N Kushnir, SJ Streatfield, V Yusibov - Vaccine, 2012 - Elsevier
Virus-like particles (VLPs) are a class of subunit vaccines that differentiate themselves from
soluble recombinant antigens by stronger protective immunogenicity associated with the …

Vaccine technologies: From whole organisms to rationally designed protein assemblies

CP Karch, P Burkhard - Biochemical pharmacology, 2016 - Elsevier
Vaccines have been the single most significant advancement in public health, preventing
morbidity and mortality in millions of people annually. Vaccine development has traditionally …

Nanomedicine in the management of microbial infection–overview and perspectives

X Zhu, AF Radovic-Moreno, J Wu, R Langer, J Shi - Nano today, 2014 - Elsevier
For more than 2 billion years, microbes have reigned on our planet, evolving or outlasting
many obstacles they have encountered. In the 20th century, this trend took a dramatic turn …