Kaposi sarcoma–associated herpesvirus: immunobiology, oncogenesis, and therapy

DP Dittmer, B Damania - The Journal of clinical …, 2016 - Am Soc Clin Investig
Kaposi sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8, is
the etiologic agent underlying Kaposi sarcoma, primary effusion lymphoma, and multicentric …

Beyond RGD: virus interactions with integrins

HAM Hussein, LR Walker, UM Abdel-Raouf… - Archives of …, 2015 - Springer
Viruses successfully infect host cells by initially binding to the surfaces of the cells, followed
by an intricate entry process. As multifunctional heterodimeric cell-surface receptor …

The synthetic antiviral drug arbidol inhibits globally prevalent pathogenic viruses

EI Pécheur, V Borisevich, P Halfmann… - Journal of …, 2016 - Am Soc Microbiol
Arbidol (ARB) is a synthetic antiviral originally developed to combat influenza viruses. ARB
is currently used clinically in several countries but not in North America. We have previously …

A novel role for phagocytosis-like uptake in herpes simplex virus entry

C Clement, V Tiwari, PM Scanlan… - The Journal of cell …, 2006 - rupress.org
It is becoming increasingly clear that herpesviruses can exploit the endocytic pathway to
infect cells, yet several important features of this process remain poorly defined. Using …

Virion proteins of Kaposi's sarcoma-associated herpesvirus

FX Zhu, JM Chong, L Wu, Y Yuan - Journal of virology, 2005 - Am Soc Microbiol
The proteins that compose a herpesvirus virion are thought to contain the functional
information required for de novo infection, as well as virion assembly and egress. To …

Cancers associated with human gammaherpesviruses

KW Wen, L Wang, JR Menke, B Damania - The FEBS journal, 2022 - Wiley Online Library
Epstein–Barr virus (EBV; human herpesvirus 4; HHV‐4) and Kaposi sarcoma‐associated
herpesvirus (KSHV; human herpesvirus 8; HHV‐8) are human gammaherpesviruses that …

Neuropilin 1 is an entry receptor for KSHV infection of mesenchymal stem cell through TGFBR1/2-mediated macropinocytosis

ZZ Lu, C Sun, X Zhang, Y Peng, Y Wang, Y Zeng… - Science …, 2023 - science.org
Kaposi's sarcoma–associated herpesvirus (KSHV) has been implicated in the pathogenesis
of Kaposi's sarcoma (KS) and other malignancies. The cellular origin of KS has been …

Concurrent expression of latent and a limited number of lytic genes with immune modulation and antiapoptotic function by Kaposi's sarcoma-associated herpesvirus …

HH Krishnan, PP Naranatt, MS Smith, L Zeng… - Journal of …, 2004 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) infection of in vitro target cells is
characterized by the expression of the latency-associated open reading frame (ORF) 73 …

The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus

AS Hahn, JK Kaufmann, E Wies, E Naschberger… - Nature medicine, 2012 - nature.com
Kaposi's sarcoma–associated herpesvirus (KSHV) is the causative agent of Kaposi's
sarcoma, a highly vascularized tumor originating from lymphatic endothelial cells, and of at …

Cell integrins: commonly used receptors for diverse viral pathogens

PL Stewart, GR Nemerow - Trends in microbiology, 2007 - cell.com
When searching for their favorite host tissues, animal viruses frequently attach to cell-surface
receptors that have key roles in normal cell physiology. Integrins are prime examples of …