Viral hepatitis is a major worldwide public health issue, affecting hundreds of millions of
people and causing substantial morbidity and mortality. The majority of the worldwide …

Background Patients with advanced cirrhosis are at high risk of developing clinically
significant portal hypertension (CSPH). We analyzed the gene expression profile of …

Background A better understanding of the evolution of cirrhosis after hepatitis C virus (HCV)
clearance is essential since the reversal of liver injury may not happen. We aimed to assess …

Unsaturated membrane phospholipids are susceptible to oxidation, either by reactive
oxygen species or enzymatically, to generate a complex mixture of peroxy and hydroxyl …

Patients with cirrhosis face a heightened risk of complications, underscoring the importance
of identification. We have developed a Connectome strategy that combines metabolites with …

Hepatitis C virus (HCV) infection alters lysophosphatidylcholine (LPC) metabolism,
enhancing viral infectivity and replication. Direct-acting antivirals (DAAs) effectively treat …

Background Combination antiretroviral therapy (ART) has transformed human
immunodeficiency virus (HIV) infection in people with HIV (PWH). However, a chronic state …

ABSTRACT Background and Aims In response to direct‐acting antivirals (DAAs) therapy,
patients who experience a decrease in hepatic venous pressure gradient (HVPG) …

Both human immunodeficiency virus (HIV) and hepatitis C virus (HCV) may induce
metabolic disorders and cause liver complications. Therefore, we aim to analyze the …

Human immunodeficiency virus (HIV) infection and highly active antiretroviral therapy use
are associated with the disruption of lipid and glucose metabolism. Herein, a sensitive and …