Radiation therapy is one of the major tools of cancer treatment, and is widely used for a
variety of malignant tumours. Radiotherapy causes DNA damage directly by ionization or …

Radiotherapy (RT) is a modality of oncologic treatment that can be used to treat
approximately 50% of all cancer patients either alone or in combination with other treatment …

Simple Summary Radiotherapy with carbon ions has been used for over 20 years in Asia
and Europe and is now planned in the USA. The physics advantages of carbon ions …

The current preclinical and clinical findings demonstrate that, in addition to the conventional
clinical and pathological indicators that have a prognostic value in radiation oncology, the …

Advances in cancer immunotherapy have offered new hope for patients with metastatic
disease. This unfolding success story has been exemplified by a growing arsenal of novel …

Radiotherapy is one of the most common treatments for oral cancer. However, in the clinic,
recurrence and metastasis of oral cancer occur after radiotherapy, and the underlying …

In solid tumors, tumor invasion and metastasis account for 90% of cancer‐related deaths.
Cell migration is steered by the lamellipodia formed at the leading edge. These lamellipodia …

Cancer cells reside amongst a complex milieu of stromal cells and structural features known
as the tumor microenvironment. Often cancer cells divert and co-opt functions of stromal …

Radiation-induced chromosomal aberrations represent an early marker of late effects,
including cell killing and transformation. The measurement of cytogenetic damage in tissues …

Purpose In multiple cell metazoans, the ability of polarized epithelial cells to convert to
motile mesenchymal cells in order to relocate to another location is governed by a unique …