High mortality rates have been reported after major amputations of a lower limb secondary
to diabetes and peripheral vascular disease. However, the mortality rates have varied …

People with diabetes develop foot ulcers because of neuropathy (sensory, motor, and
autonomic deficits), ischaemia, or both. The initiating injury may be from acute mechanical or …

OBJECTIVE: To determine mortality rates after a first lower limb amputation and explore the
rates for different subpopulations. METHODS: Retrospective cohort study of all people who …

BACKGROUND: Little is known regarding the contemporary outcomes of older patients with
peripheral artery disease (PAD) undergoing major lower extremity (LE) amputation in the …

BACKGROUND: Despite being a major determinant of functional independence, ambulation
after major limb amputation has not been well studied. The purpose, therefore, of this study …

Objectives: This study sought to characterize temporal trends, patient-specific factors, and
geographic variation associated with amputation in patients with lower-extremity peripheral …

Background The purpose of this study was to investigate the prevalence of lower extremity
amputation in England, to establish the associated mortality, and to determine the …

Peripheral artery disease affects over eight million Americans and is associated with an
increased risk of mortality, cardiovascular disease, functional limitation, and limb loss. In its …

BACKGROUND: Major amputation is a dreaded event with high mortality and morbidity.
However, few studies have investigated the epidemiology of amputation in the elderly over …

Background Owing to the aging population, the number of elderly patients with critical limb
ischemia (CLI) has increased. The consequence of amputation is immense. However, at the …