Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation

JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

[HTML][HTML] Cardiovascular disease and brain health: Focus on white matter hyperintensities

F Moroni, E Ammirati, MA Rocca, M Filippi… - IJC heart & …, 2018 - Elsevier
Diseases affecting the brain contribute to a substantial proportion of morbidity and mortality
in the general population. Conditions such as stroke, dementia and cognitive impairment …

Association of white matter hyperintensities and cardiovascular disease: the importance of microcirculatory disease

F Moroni, E Ammirati, AH Hainsworth… - Circulation …, 2020 - Am Heart Assoc
Cardiac and cerebrovascular diseases are currently the leading causes of mortality and
disability worldwide. Both the heart and brain display similar vascular anatomy, with large …

Covert brain infarction: towards precision medicine in research, diagnosis, and therapy for a silent pandemic

TR Meinel, J Kaesmacher, L Roten, U Fischer - Stroke, 2020 - Am Heart Assoc
The use of medical brain imaging has increased dra-matically over the past decade and up
to 20 magnetic resonance imaging (MRI) and 30 computed tomography (CT) exams are now …

Emerging role of white matter lesions in cerebrovascular disease

A Rastogi, R Weissert… - European Journal of …, 2021 - Wiley Online Library
White matter lesions have been implicated in the setting of stroke, dementia, intracerebral
haemorrhage, several other cerebrovascular conditions, migraine, various …

The association between carotid artery atherosclerosis and silent brain infarction: a systematic review and meta-analysis

C Finn, AE Giambrone, G Gialdini, D Delgado… - Journal of Stroke and …, 2017 - Elsevier
Background Carotid atherosclerosis is responsible for~ 20% of ischemic strokes, but it is
unclear whether carotid disease is associated with the presence of downstream silent brain …

The association of intracranial atherosclerosis with cerebral small vessel disease imaging markers: A high-resolution magnetic resonance imaging study

KL Zhu, ZY Shang, B Liu, Y Wang, J Li, BQ Yang… - Scientific Reports, 2023 - nature.com
To evaluate the association of intracranial non-stenotic atherosclerotic plaque with cerebral
small vessel disease (CSVD) imaging markers in a CSVD population using 3.0 T high …

Brain volume, energy balance, and cardiovascular health in two nonindustrial South American populations

H Kaplan, PL Hooper, M Gatz… - Proceedings of the …, 2023 - National Acad Sciences
Little is known about brain aging or dementia in nonindustrialized environments that are
similar to how humans lived throughout evolutionary history. This paper examines brain …

Carotid atherosclerosis, dilation, and stiffness relate to cerebral small vessel disease

FF Zhai, M Yang, Y Wei, M Wang, Y Gui, F Han… - Neurology, 2020 - AAN Enterprises
Objective To investigate the association of carotid atherosclerosis, dilation, and stiffness with
imaging markers of cerebral small vessel disease (CSVD) in a community-based sample …

Atherosclerosis: the culprit and co-victim of vascular dementia

YT Huang, FF Hong, SL Yang - Frontiers in neuroscience, 2021 - frontiersin.org
Vascular dementia (VD), a cerebrovascular disease which causes cognitive impairment, is
one of the significant factors that affects the quality of senectitude. Atherosclerosis (AS) is a …