New avenues for the treatment of Huntington's disease

A Kim, K Lalonde, A Truesdell, P Gomes Welter… - International journal of …, 2021 - mdpi.com
Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG expansion in
the HD gene. The disease is characterized by neurodegeneration, particularly in the striatum …

Huntington disease: pathogenesis and treatment

P Dayalu, RL Albin - Neurologic clinics, 2015 - neurologic.theclinics.com
Huntington disease (HD) is an autosomal dominant inherited neurodegenerative disease
characterized by progressive motor, behavioral, and cognitive decline, resulting in death …

Cognitive impairment in Huntington disease: diagnosis and treatment

JS Paulsen - Current neurology and neuroscience reports, 2011 - Springer
Cognition has been well characterized in the various stages of Huntington disease (HD) as
well as in the prodrome before the motor diagnosis is given. Although the clinical diagnosis …

Huntington's disease—update on treatments

KJ Wyant, AJ Ridder, P Dayalu - Current neurology and neuroscience …, 2017 - Springer
Huntington's disease (HD) is an autosomal dominantly inherited neurodegenerative disease
characterized by progressive motor, behavioral, and cognitive decline, ending in death …

The neuropsychology of Huntington's disease

JS Snowden - Archives of Clinical Neuropsychology, 2017 - academic.oup.com
Huntington's disease is an inherited, degenerative brain disease, characterized by
involuntary movements, cognitive disorder and neuropsychiatric change. Men and women …

Huntington disease: a single-gene degenerative disorder of the striatum

PC Nopoulos - Dialogues in clinical neuroscience, 2016 - Taylor & Francis
Huntington disease (HD) is an autosomal dominant, neurodegenerative disorder with a
primary etiology of striatal pathology. The Huntingtin gene (HTT) has a unique feature of a …

Longitudinal psychiatric symptoms in prodromal Huntington's disease: a decade of data

EA Epping, JI Kim, D Craufurd… - American Journal of …, 2016 - Am Psychiatric Assoc
Objective: Psychiatric symptoms are a significant aspect of Huntington's disease, an
inherited neurodegenerative illness. The presentation of these symptoms is highly variable …

Focusing the pivotal role of nanotechnology in Huntington's disease: an insight into the recent advancements

S Singh, Hema, N Sharma, M Sachdeva, T Behl… - … Science and Pollution …, 2022 - Springer
Neurodegeneration is the loss of neuronal capacity and structure over time which causes
neurodegenerative disorders like Alzheimer, amyotrophic lateral sclerosis, Parkinson, and …

Mild cognitive impairment in prediagnosed Huntington disease

K Duff, J Paulsen, J Mills, LJ Beglinger, DJ Moser… - Neurology, 2010 - AAN Enterprises
Background: Cognitive decline has been reported in Huntington disease (HD), as well as in
the period before diagnosis of motor symptoms (ie, pre-HD). However, the severity …

“Frontal” behaviors before the diagnosis of Huntington's disease and their relationship to markers of disease progression: evidence of early lack of awareness

K Duff, JS Paulsen, LJ Beglinger… - The Journal of …, 2010 - Am Neuropsych Assoc
Huntington's disease is an autosomal dominant, progressive neurological disorder that is
characterized by motor disturbance, cognitive dysfunction, and psychiatric symptomatology …