Microfluidic technologies have been extensively investigated in recent years for developing
organ-on-a-chip-devices as robust in vitro models aiming to recapitulate organ 3D …

Engineered metal/mineral, lipid and biochemical macromolecule nanomaterials (NMs) have
potential applications in food. Methodologies for the assessment of NM digestion and …

Esophageal squamous-cell carcinoma (ESCC), one of the most prevalent and lethal
malignant disease, has a complex but unknown tumor ecosystem. Here, we investigate the …

The intestine forms the largest interface between the environment and the human organism.
Its integrity and functioning are crucial for the uptake of nutrients while preventing access of …

The use of silver nanoparticles in food, food contact materials, dietary supplements and
cosmetics has increased significantly owing to their antibacterial and antifungal properties …

The in vitro 3D culture of intestinal epithelium is a valuable resource in the study of its
function. Organoid culture exploits stem cells' ability to regenerate and produce …

Organoids are three‐dimensional self‐aggregating structures generated from stem cells
(SCs) or progenitor cells in a process that recapitulates molecular and cellular stages of …

Our focus was to develop a three-dimensional (3D) human dynamic in vitro tissue model that
mimics the natural microenvironment of the small intestine. We co-cultured human Caco-2 …

The majority of intestinal in vitro screening models use cell lines that do not reflect the
complexity of the human intestinal tract and hence often fail to accurately predict intestinal …

In this study, we tested the hypothesis that milk oligosaccharides may contribute not only to
selective growth of bifidobacteria, but also to their specific adhesive ability. Human milk …