Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes

LDJ Bos, LB Ware - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is a common clinical syndrome of acute
respiratory failure as a result of diffuse lung inflammation and oedema. ARDS can be …

Redefining critical illness

DM Maslove, B Tang, M Shankar-Hari, PR Lawler… - Nature medicine, 2022 - nature.com
Research and practice in critical care medicine have long been defined by syndromes,
which, despite being clinically recognizable entities, are, in fact, loose amalgams of …

ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

G Grasselli, CS Calfee, L Camporota, D Poole… - Intensive care …, 2023 - Springer
The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the
European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to …

A new global definition of acute respiratory distress syndrome

MA Matthay, Y Arabi, AC Arroliga… - American journal of …, 2024 - atsjournals.org
Background: Since publication of the 2012 Berlin definition of acute respiratory distress
syndrome (ARDS), several developments have supported the need for an expansion of the …

Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management

EA Gorman, CM O'Kane, DF McAuley - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …

[HTML][HTML] COVID-19-associated acute respiratory distress syndrome: is a different approach to management warranted?

E Fan, JR Beitler, L Brochard, CS Calfee… - The Lancet …, 2020 - thelancet.com
The COVID-19 pandemic has seen a surge of patients with acute respiratory distress
syndrome (ARDS) in intensive care units across the globe. As experience of managing …

Practitioner's guide to latent class analysis: methodological considerations and common pitfalls

P Sinha, CS Calfee, KL Delucchi - Critical care medicine, 2021 - journals.lww.com
Latent class analysis is a probabilistic modeling algorithm that allows clustering of data and
statistical inference. There has been a recent upsurge in the application of latent class …

Is a “cytokine storm” relevant to COVID-19?

P Sinha, MA Matthay, CS Calfee - JAMA internal medicine, 2020 - jamanetwork.com
In its most severe form, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
virus that causes coronavirus disease 2019 (COVID-19), leads to a life-threatening …

Fluid overload and mortality in adult critical care patients—a systematic review and meta-analysis of observational studies

AS Messmer, C Zingg, M Müller, JL Gerber… - Critical care …, 2020 - journals.lww.com
Objective: Fluid administration in combination with the increase in vasopermeability induced
by critical illness often results in significant fluid overload in critically ill patients. Recent …

Personalized mechanical ventilation in acute respiratory distress syndrome

P Pelosi, L Ball, CSV Barbas, R Bellomo, KEA Burns… - Critical care, 2021 - Springer
A personalized mechanical ventilation approach for patients with adult respiratory distress
syndrome (ARDS) based on lung physiology and morphology, ARDS etiology, lung imaging …