Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …

Aging is a natural process that is associated with cognitive decline as well as functional and
social impairments. One structure of particular interest when considering aging and …

The dentate gyrus (DG) gates neocortical information flow to the hippocampus. Intriguingly,
the DG also produces adult-born dentate granule cells (abDGCs) throughout the lifespan …

Significant progress has been made in understanding the neurobiological mechanisms
through which exercise protects and restores the brain. In this feature review, we integrate …

Mounting evidence suggests that neuronal activity influences myelination, potentially
allowing for experience-driven modulation of neural circuitry. The degree to which neuronal …

Adult neurogenesis in the hippocampus is a notable process due not only to its uniqueness
and potential impact on cognition but also to its localized vertical integration of different …

In the embryonic and adult brain, neural stem cells proliferate and give rise to neurons and
glia through highly regulated processes. Epigenetic mechanisms—including DNA and …

The hippocampus, a brain area critical for learning and memory, is especially vulnerable to
damage at early stages of Alzheimer's disease (AD). Emerging evidence has indicated that …

The brain is the key organ of stress reactivity, coping, and recovery processes. Within the
brain, a distributed neural circuitry determines what is threatening and thus stressful to the …

Enhancing neurogenesis within the hippocampal dentate gyrus (DG) is critical for
maintaining brain development and function in many neurological diseases. However, the …