Congenital anomalies of the kidney and urinary tract (CAKUT) comprise a large variety of
malformations that arise from defective kidney or urinary tract development and frequently …

Genes of the Sprouty family (Spry1-4) restrain signaling by certain receptor tyrosine kinases.
Consequently, these genes participate in several developmental processes and function as …

The Wolffian ducts (WD) are paired epithelial tubules central to the development of the
mammalian genitourinary tract. Outgrowths from the WD known as the ureteric buds (UB) …

Sprouty proteins are widely accepted modulators of receptor tyrosine kinase-associated
pathways and fulfill diversified roles in cancerogenesis dependent on the originating cells. In …

The kidney presents in the highest degree the phenomenon of sensibility; the power of
reacting to various stimuli in a direction which is appropriate for the survival of the organism; …

Craniosynostosis, the premature fusion of the cranial sutures, affects~ 1 in 2,000 live births. It
is a heterogenous disorder with documented monogenic, polygenic, chromosomal, and …