Investigations into bacterial protein glycosylation continue to progress rapidly. It is now
established that bacteria possess both N-linked and O-linked glycosylation pathways that …

The pathogenic clostridia cause many human and animal diseases, which typically arise as
a consequence of the production of potent exotoxins. Among the enterotoxic clostridia …

The recent development of the ClosTron Group II intron directed mutagenesis tool for
Clostridium has advanced genetics in this genus, and here we present several significant …

Clostridium difficile infection is the leading cause of antibiotic-and healthcare-associated
diarrhea, and its containment and treatment imposes a significant financial burden …

Recent years have witnessed a rapid growth in the number and diversity of prokaryotic
proteins shown to carry N‐and/or O‐glycans, with protein glycosylation now considered as …

Clostridium difficile is the prominent etiological agent of healthcare-associated diarrhea. The
disease symptoms range from mild diarrhea to life-threatening pseudomembranous colitis …

Clostridium difficile-associated disease is increasing in incidence and is costly to treat. Our
understanding of how this organism senses its entry into the host and adapts for growth in …

Glycosylation of proteins is one of the most prevalent post-translational modifications
occurring in nature, with a wide repertoire of biological implications. Pathways for the main …

Humans have been increasingly recognized as being superorganisms, living in close
contact with a microbiota on all their mucosal surfaces. However, most studies on the human …

Clostridium difficile is a Gram-positive anaerobic, spore-forming bacillus that is the leading
cause of nosocomial diarrhoea worldwide. We demonstrate that C. difficile aggregates and …