Soft lithography in biology and biochemistry

GM Whitesides, E Ostuni, S Takayama… - Annual review of …, 2001 - annualreviews.org
▪ Abstract Soft lithography, a set of techniques for microfabrication, is based on printing and
molding using elastomeric stamps with the patterns of interest in bas-relief. As a technique …

Physics and applications of microfluidics in biology

DJ Beebe, GA Mensing… - Annual review of …, 2002 - annualreviews.org
▪ Abstract Fluid flow at the microscale exhibits unique phenomena that can be leveraged to
fabricate devices and components capable of performing functions useful for biological …

Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence

J Guck, S Schinkinger, B Lincoln, F Wottawah, S Ebert… - Biophysical journal, 2005 - cell.com
The relationship between the mechanical properties of cells and their molecular architecture
has been the focus of extensive research for decades. The cytoskeleton, an internal polymer …

[HTML][HTML] The optical stretcher: a novel laser tool to micromanipulate cells

J Guck, R Ananthakrishnan, H Mahmood, TJ Moon… - Biophysical journal, 2001 - cell.com
When a dielectric object is placed between two opposed, nonfocused laser beams, the total
force acting on the object is zero but the surface forces are additive, thus leading to a …

Systems biology and new technologies enable predictive and preventative medicine

L Hood, JR Heath, ME Phelps, B Lin - Science, 2004 - science.org
Systems approaches to disease are grounded in the idea that disease-perturbed protein
and gene regulatory networks differ from their normal counterparts; we have been pursuing …

Hydrodynamic focusing on a silicon chip: mixing nanoliters in microseconds

JB Knight, A Vishwanath, JP Brody, RH Austin - Physical review letters, 1998 - APS
We describe the formation and control of nanoscale, submerged fluid jets. The focusing
process necessary to achieve these small length scales is characterized experimentally and …

A microfabricated fluorescence-activated cell sorter

AY Fu, C Spence, A Scherer, FH Arnold… - Nature …, 1999 - nature.com
We have demonstrated a disposable microfabricated fluorescence-activated cell sorter
(μFACS) for sorting various biological entities. Compared with conventional FACS …

Structural lubricity in soft and hard matter systems

A Vanossi, C Bechinger, M Urbakh - Nature Communications, 2020 - nature.com
Over the recent decades there has been tremendous progress in understanding and
controlling friction between surfaces in relative motion. However the complex nature of the …

Blood-on-a-chip

M Toner, D Irimia - Annu. Rev. Biomed. Eng., 2005 - annualreviews.org
▪ Abstract Accurate, fast, and affordable analysis of the cellular component of blood is of
prime interest for medicine and research. Yet, most often sample preparation procedures for …

Microfluidic devices for cellomics: a review

H Andersson, A Van den Berg - Sensors and actuators B: Chemical, 2003 - Elsevier
A review of microfluidic devices for cellomics is presented. After a brief description of the
historical background of Lab-on-Chip (LOC) devices, different areas are reviewed. Devices …