The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes

KH Al-Gubory, PA Fowler, C Garrel - … journal of biochemistry & cell biology, 2010 - Elsevier
Reactive oxygen species (ROS) are generated as by-products of aerobic respiration and
metabolism. Mammalian cells have evolved a variety of enzymatic mechanisms to control …

The role of antioxidant enzymes in the ovaries

S Wang, G He, M Chen, T Zuo, W Xu… - Oxidative medicine and …, 2017 - Wiley Online Library
Proper physiological function of the ovaries is very important for the entire female
reproductive system and overall health. Reactive oxygen species (ROS) are generated as …

Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

CJ Harvey, RK Thimmulappa, A Singh, DJ Blake… - Free Radical Biology …, 2009 - Elsevier
Nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) is the primary transcription factor
protecting cells from oxidative stress by regulating cytoprotective genes, including the …

Oxidative damage increases and antioxidant gene expression decreases with aging in the mouse ovary

J Lim, U Luderer - Biology of reproduction, 2011 - academic.oup.com
Oxidative stress has been implicated in various aspects of aging, but the role of oxidative
stress in ovarian aging remains unclear. Our previous studies have shown that the initiation …

Regulation of sperm function by reactive oxygen species

WCL Ford - Human reproduction update, 2004 - academic.oup.com
Sperm capacitation can be increased by the addition of reactive oxygen species (ROS) and
decreased by antioxidants. Broadly consistent results have been achieved with a wide …

[HTML][HTML] Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system

J Fujii, Y Iuchi, F Okada - Reproductive biology and endocrinology, 2005 - Springer
Controlled oxidation, such as disulfide bond formation in sperm nuclei and during ovulation,
plays a fundamental role in mammalian reproduction. Excess oxidation, however, causes …

Influence of selenium sources on age-related and mild heat stress-related changes of blood and liver glutathione redox cycle in broiler chickens (Gallus domesticus)

KZ Mahmoud, FW Edens - … and Physiology Part B: Biochemistry and …, 2003 - Elsevier
Selenium is an essential trace element that up-regulates a major component of the
antioxidant defense mechanism by controlling the body's glutathione (GSH) pool and its …

Knockout of the transcription factor NRF2 disrupts spermatogenesis in an age-dependent manner

BN Nakamura, G Lawson, JY Chan, J Banuelos… - Free Radical Biology …, 2010 - Elsevier
Oxidative stress occurs when generation of reactive oxygen species (ROS) overwhelms
antioxidant defenses. Oxidative stress has been associated with male infertility. The …

Effect of dietary isoleucine on the immunity, antioxidant status, tight junctions and microflora in the intestine of juvenile Jian carp (Cyprinus carpio var. Jian)

J Zhao, L Feng, Y Liu, W Jiang, P Wu, J Jiang… - Fish & Shellfish …, 2014 - Elsevier
This study was conducted to investigate the effects of dietary isoleucine (Ile) on the immune
response, antioxidant status, tight junctions, and microbial population in the intestine of …

Exogenous phospholipids supplementation improves growth and modulates immune response and physical barrier referring to NF-κB, TOR, MLCK and Nrf2 signaling …

YP Chen, WD Jiang, Y Liu, J Jiang, P Wu… - Fish & shellfish …, 2015 - Elsevier
This study was conducted to investigate the effects of dietary phospholipids (PL) on the
growth performance, intestinal enzyme activity and immune response and intestinal physical …