New neurons for'survival of the fittest'
G Kempermann - Nature reviews neuroscience, 2012 - nature.com
Adult neurogenesis is often considered an archaic trait that has undergone a'phylogenetic
reduction'from amphibian ancestors to humans. However, adult neurogenesis in the …
reduction'from amphibian ancestors to humans. However, adult neurogenesis in the …
Brain size and limits to adult neurogenesis
MF Paredes, SF Sorrells… - Journal of …, 2016 - Wiley Online Library
The walls of the cerebral ventricles in the developing embryo harbor the primary neural stem
cells from which most neurons and glia derive. In many vertebrates, neurogenesis continues …
cells from which most neurons and glia derive. In many vertebrates, neurogenesis continues …
Safety evaluation of a clinical focused ultrasound system for neuronavigation guided blood-brain barrier opening in non-human primates
An emerging approach with potential in improving the treatment of neurodegenerative
diseases and brain tumors is the use of focused ultrasound (FUS) to bypass the blood–brain …
diseases and brain tumors is the use of focused ultrasound (FUS) to bypass the blood–brain …
Immature excitatory neurons develop during adolescence in the human amygdala
The human amygdala grows during childhood, and its abnormal development is linked to
mood disorders. The primate amygdala contains a large population of immature neurons in …
mood disorders. The primate amygdala contains a large population of immature neurons in …
The PSA-NCAM-positive “immature” neurons: an old discovery providing new vistas on brain structural plasticity
L Bonfanti, T Seki - Cells, 2021 - mdpi.com
Studies on brain plasticity have undertaken different roads, tackling a wide range of
biological processes: from small synaptic changes affecting the contacts among neurons at …
biological processes: from small synaptic changes affecting the contacts among neurons at …
Brain plasticity in humans and model systems: advances, challenges, and future directions
L Bonfanti, CJ Charvet - International journal of molecular sciences, 2021 - mdpi.com
Plasticity, and in particular, neurogenesis, is a promising target to treat and prevent a wide
variety of diseases (eg, epilepsy, stroke, dementia). There are different types of plasticity …
variety of diseases (eg, epilepsy, stroke, dementia). There are different types of plasticity …
Phylogenetic variation in cortical layer II immature neuron reservoir of mammals
The adult mammalian brain is mainly composed of mature neurons. A limited amount of
stem cell-driven neurogenesis persists in postnatal life and is reduced in large-brained …
stem cell-driven neurogenesis persists in postnatal life and is reduced in large-brained …
Doublecortin-expressing neurons in human cerebral cortex layer II and amygdala from infancy to 100 years old
YN Li, DD Hu, XL Cai, Y Wang, C Yang, J Jiang… - Molecular …, 2023 - Springer
A cohort of morphologically heterogenous doublecortin immunoreactive (DCX+)“immature
neurons” has been identified in the cerebral cortex largely around layer II and the amygdala …
neurons” has been identified in the cerebral cortex largely around layer II and the amygdala …
Cancer stem cell contribution to glioblastoma invasiveness
B Ortensi, M Setti, D Osti, G Pelicci - Stem cell research & therapy, 2013 - Springer
Glioblastoma (GBM) is the most aggressive and lethal brain tumor in adults. Its invasive
nature currently represents the most challenging hurdle to surgical resection. The …
nature currently represents the most challenging hurdle to surgical resection. The …
Neural stem cell niches in health and diseases
Presence of neural stem cells in adult mammalian brains, including human, has been clearly
demonstrated by several studies. The functional significance of adult neurogenesis is slowly …
demonstrated by several studies. The functional significance of adult neurogenesis is slowly …