Brain SPECT as a biomarker of neurodegeneration in dementia in the era of molecular imaging: still a valid option?

R Ferrando, A Damian - Frontiers in Neurology, 2021 - frontiersin.org
Biomarkers are playing a progressively leading role in both clinical practice and scientific
research in dementia. Although amyloid and tau biomarkers have gained ground in the …

Neuroimaging Techniques in Differentiating Parkinson's Disease from Drug-Induced Parkinsonism: A Comprehensive Review

J Pitton Rissardo, ALF Caprara - Clinics and Practice, 2023 - mdpi.com
Neuroimaging can provide significant benefits in evaluating patients with movement
disorders associated with drugs. This literature review describes neuroimaging techniques …

Theta burst magnetic stimulation improves Parkinson's-related cognitive impairment: a randomised controlled study

W He, JC Wang, PY Tsai - Neurorehabilitation and Neural …, 2021 - journals.sagepub.com
Background. Evidence remains mixed as to the effectiveness of repetitive transcranial
magnetic stimulation (rTMS) in treating mild cognitive impairment (MCI) in patients with …

Fluorescence-tagged salivary small extracellular vesicles as a nanotool in early diagnosis of Parkinson's disease

S Rastogi, K Rani, S Rai, R Singh, PS Bharti, V Sharma… - BMC medicine, 2023 - Springer
Background Parkinson's disease is generally asymptomatic at earlier stages. At an early
stage, there is an extensive progression in the neuropathological hallmarks, although, at this …

Radiation interactions with biological systems

MT Islam - International journal of radiation biology, 2017 - Taylor & Francis
Purpose: The use of radiation, especially ionizing radiation (IR), is currently attracting great
attention in the field of medical sciences. However, it should be mentioned that IR has both …

[HTML][HTML] 99mTc-TRODAT-1 SPECT imaging in early and late onset Parkinson's disease

P Sasannezhad, AG Juibary, K Sadri… - Asia Oceania Journal …, 2017 - ncbi.nlm.nih.gov
Objective (s): 99m Tc-TRODAT-1, which binds to the dopamine transporter, could be used to
image the dopaminergic system in diagnosis of Parkinson's disease (PD). PD can be …

SPG11‐related parkinsonism: Clinical profile, molecular imaging and l‐dopa response

I Faber, ARM Martinez, CR Martins Jr… - Movement …, 2018 - Wiley Online Library
Background: Molecular imaging has proven to be a powerful tool to elucidate degenerated
paths in a wide variety of neurological diseases and has not been systematically studied in …

Comparative performance of 99mTc-TRODAT-1 SPECT/CT and 18F-FDOPA PET/CT imaging in patients with Parkinson's disease, Parkinson-plus syndrome, and …

A Sood, J Shukla, R Shree, R Vatsa… - Clinical Nuclear …, 2021 - journals.lww.com
Purpose The aim of this study was to assess the utility of presynaptic dopaminergic imaging
using 99m Tc-TRODAT-1 SPECT/CT and 18 F-FDOPA PET/CT and compare their …

Production and clinical applications of radiopharmaceuticals and medical radioisotopes in Iran

AR Jalilian, D Beiki, A Hassanzadeh-Rad… - Seminars in Nuclear …, 2016 - Elsevier
During past 3 decades, nuclear medicine has flourished as vibrant and independent
medical specialty in Iran. Since that time, more than 200 nuclear physicians have been …

Synthesis, biological evaluation and preclinical study of a novel 99mTc-peptide: A targeting probe of amyloid-β plaques as a possible diagnostic agent for Alzheimer's …

S Jokar, H Behnammanesh, M Erfani, M Sharifzadeh… - Bioorganic …, 2020 - Elsevier
With respect to the main role of amyloid-β (Aβ) plaques as one of the pathological hallmarks
in the brain of Alzheimer's patients, the development of new imaging probes for targeted …