Recent progress regarding kaempferol for the treatment of various diseases

JIE Ren, Y Lu, Y Qian, B Chen… - Experimental and …, 2019 - spandidos-publications.com
Kaempferol, also known as kaempferol‑3 or kaempferide, is a flavonoid compound that
naturally occurs in tea, as well as numerous common vegetables and fruits, including beans …

Traditional usages, botany, phytochemistry, pharmacology and toxicology of Polygonum multiflorum Thunb.: a review

L Lin, B Ni, H Lin, M Zhang, X Li, X Yin, C Qu… - Journal of …, 2015 - Elsevier
Abstract Ethnopharmacological relevance Polygonum multiflorum Thunb., which is known
as Heshouwu (何首乌 in Chinese) in China. It is traditionally valued and reported for hair …

Natural products against Alzheimer's disease: Pharmaco-therapeutics and biotechnological interventions

A Dey, R Bhattacharya, A Mukherjee… - Biotechnology advances, 2017 - Elsevier
Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease
associated with memory and cognition impairment ultimately leading to death. It is the …

Kaempferol as a potential neuroprotector in Alzheimer's disease

HR Nejabati, L Roshangar - Journal of Food Biochemistry, 2022 - Wiley Online Library
Abstract Alzheimer's disease (AD), the most prevalent neurodegenerative disorder, is largely
associated with cognitive disability, amnesia, and abnormal behavior, which accounts for …

Kaempferol attenuates the glutamate-induced oxidative stress in mouse-derived hippocampal neuronal HT22 cells

EJ Yang, GS Kim, M Jun, KS Song - Food & function, 2014 - pubs.rsc.org
It is thought that the neuronal cell loss caused by oxidative stress is the primary mechanism
underlying the pathogenesis of several neurodegenerative disorders. Glutamate is an …

[HTML][HTML] Bone marrow stromal cells-derived exosomes reduce neurological damage in traumatic brain injury through the miR-124-3p/p38 MAPK/GLT-1 axis

Z Zhuang, M Liu, Z Dai, J Luo, B Zhang, H Yu… - Experimental …, 2023 - Elsevier
Background Mounting evidence indicates that stem cell-derived exosomal miRNAs have
therapeutic effects on traumatic brain injury (TBI). This research is focused on exploring the …

Emodin from Polygonum multiflorum ameliorates oxidative toxicity in HT22 cells and deficits in photothrombotic ischemia

SM Ahn, HN Kim, YR Kim, YW Choi, CM Kim… - Journal of …, 2016 - Elsevier
Abstract Ethnopharmacological relevance Polygonum multiflorum Thunb. has been used
widely in East Asia in treatment of diseases associated with aging. Emodin, an active …

Liquiritin modulates ERK‑and AKT/GSK‑3β‑dependent pathways to protect against glutamate‑induced cell damage in differentiated PC12 cells

L Teng, Q Meng, J Lu, J Xie… - Molecular …, 2014 - spandidos-publications.com
Glutamate has a key role in the neuronal cell damage associated with Alzheimer's and
Parkinson's diseases. Liquiritin (LQ), a major constituent of Glycyrrhiza Radix, possesses …

Urine metabolomics study on the liver injury in rats induced by raw and processed Polygonum multiflorum integrated with pattern recognition and pathways analysis

C Zhang, M Niu, Q Li, Y Zhao, Z Ma, Y Xiong… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Polygonum multiflorum L. is a famous traditional Chinese
medicine that has always been perceived to be safe. Recently, the increasing case reports …

TSG (2, 3, 5, 4′‐Tetrahydroxystilbene‐2‐O‐β‐D‐glucoside) from the Chinese herb polygonum multiflorum increases life span and stress resistance of caenorhabditis …

C Büchter, L Zhao, S Havermann… - Oxidative Medicine …, 2015 - Wiley Online Library
2, 3, 5, 4′‐Tetrahydroxystilbene‐2‐O‐β‐D‐glucoside (TSG) was isolated from Polygonum
multiflorum, a plant which is traditionally used as an anti‐ageing drug. We have analysed …