RNA-based therapies have catalyzed a revolutionary transformation in the biomedical
landscape, offering unprecedented potential in disease prevention and treatment. However …

RNA has emerged as a revolutionary and important tool in the battle against emerging
infectious diseases, with roles extending beyond its applications in vaccines, in which it is …

The current SARS-CoV-2 pandemic forms a major global health burden. Although protective
vaccines are available, concerns remain as new virus variants continue to appear. CRISPR …

Functional nucleic acids (FNAs) have attracted increasing attention in recent years due to
their diverse physiological functions. The understanding of their conformational recognition …

The COVID-19 pandemic has posed a severe threat to human life and the global economy.
Although conventional treatments, including vaccines, antibodies, and small-molecule …

Nucleic acids in the form of siRNA, antisense oligonucleotides or mRNA are currently
explored as new promising modalities in the pharmaceutical industry. Particularly, the …

Traditionally, antiviral drugs target viral enzymes and or structural proteins, identified
through large drug screens or rational drug design. The screening, chemical optimisation …

Although the COVID-19 pandemic was declared no longer a global emergency by the World
Health Organization in May 2023, SARS-CoV-2 is still infecting people across the world …

Lipid nanoparticles (LNPs) have emerged as a powerful platform for RNA delivery; the
chemical engineering of LNP for efficient delivery of RNA into cytosol remains critical but …

Nukleinsäuren in Form von siRNA, Antisense‐Oligonukleotiden oder mRNA werden derzeit
als neue vielversprechende Modalitäten in der pharmazeutischen Industrie erforscht …