A review of cytokine-based pathophysiology of Long COVID symptoms

RN Low, RJ Low, A Akrami - Frontiers in Medicine, 2023 - frontiersin.org
The Long COVID/Post Acute Sequelae of COVID-19 (PASC) group includes patients with
initial mild-to-moderate symptoms during the acute phase of the illness, in whom recovery is …

Long COVID: major findings, mechanisms and recommendations

HE Davis, L McCorkell, JM Vogel… - Nature Reviews …, 2023 - nature.com
Long COVID is an often debilitating illness that occurs in at least 10% of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. More than 200 symptoms …

Development of a definition of postacute sequelae of SARS-CoV-2 infection

T Thaweethai, SE Jolley, EW Karlson, EB Levitan… - Jama, 2023 - jamanetwork.com
Importance SARS-CoV-2 infection is associated with persistent, relapsing, or new symptoms
or other health effects occurring after acute infection, termedpostacute sequelae of SARS …

[HTML][HTML] Muscle abnormalities worsen after post-exertional malaise in long COVID

B Appelman, BT Charlton, RP Goulding… - Nature …, 2024 - nature.com
A subgroup of patients infected with SARS-CoV-2 remain symptomatic over three months
after infection. A distinctive symptom of patients with long COVID is post-exertional malaise …

Persistent complement dysregulation with signs of thromboinflammation in active Long Covid

C Cervia-Hasler, SC Brüningk, T Hoch, B Fan, G Muzio… - Science, 2024 - science.org
Long Covid is a debilitating condition of unknown etiology. We performed multimodal
proteomics analyses of blood serum from COVID-19 patients followed up to 12 months after …

Low vitamin D levels are associated with long COVID syndrome in COVID-19 survivors

L di Filippo, S Frara, F Nannipieri… - The Journal of …, 2023 - academic.oup.com
Context Long COVID is an emerging syndrome affecting 50% to 70% of COVID-19 survivors
that still lacks predicting factors. Objective Due to the extraskeletal effects of vitamin D, we …

Structural brain changes in patients with post-COVID fatigue: a prospective observational study

J Heine, K Schwichtenberg, TJ Hartung, S Rekers… - …, 2023 - thelancet.com
Background Post-COVID syndrome is a severe long-term complication of COVID-19.
Although fatigue and cognitive complaints are the most prominent symptoms, it is unclear …

[HTML][HTML] Dysregulated autoantibodies targeting vaso-and immunoregulatory receptors in Post COVID Syndrome correlate with symptom severity

F Sotzny, IS Filgueiras, C Kedor, H Freitag… - Frontiers in …, 2022 - frontiersin.org
Most patients with Post COVID Syndrome (PCS) present with a plethora of symptoms without
clear evidence of organ dysfunction. A subset of them fulfills diagnostic criteria of myalgic …

Long-term symptom severity and clinical biomarkers in post-COVID-19/chronic fatigue syndrome: results from a prospective observational cohort

F Legler, L Meyer-Arndt, L Mödl, C Kedor… - …, 2023 - thelancet.com
Summary Background Post-COVID-19 syndrome (PCS) is characterised by a wide range of
symptoms, primarily fatigue and exertion intolerance. While disease courses in the early …

Female reproductive health impacts of Long COVID and associated illnesses including ME/CFS, POTS, and connective tissue disorders: a literature review

B Pollack, E von Saltza, L McCorkell… - Frontiers in …, 2023 - frontiersin.org
Long COVID disproportionately affects premenopausal women, but relatively few studies
have examined Long COVID's impact on female reproductive health. We conduct a review of …