Marine natural products

AR Carroll, BR Copp, RA Davis, RA Keyzers… - Natural product …, 2022 - pubs.rsc.org
Covering: 2020 This review covers the literature published in 2020 for marine natural
products (MNPs), with 757 citations (747 for the period January to December 2020) referring …

Natural products and their analogues acting against Mycobacterium tuberculosis: A recent update

G Kumar - Drug Development Research, 2023 - Wiley Online Library
Tuberculosis (TB) remains one of the deadliest infectious diseases caused by
Mycobacterium tuberculosis (M. tb). It is responsible for significant causes of mortality and …

Drug repurposing strategy II: from approved drugs to agri-fungicide leads

JX An, Y Ma, WB Zhao, YM Hu, YR Wang… - The Journal of …, 2023 - nature.com
Epidemic diseases of crops caused by fungi deeply affected the course of human history
and processed a major restriction on social and economic development. However, with the …

Structural and Biological Insights into the Hot‐Spot Marine Natural Products Reported from 2012 to 2021

M Liu, X Zhang, G Li - Chinese Journal of Chemistry, 2022 - Wiley Online Library
Comprehensive Summary The vast marine ecosystem contains a sea of natural products,
which are potential model molecules for new drug development. With more than one …

Metabolomic comparison and assessment of co-cultivation and a heat-killed inducer strategy in activation of cryptic biosynthetic pathways

L Liang, G Wang, B Haltli, DH Marchbank… - Journal of Natural …, 2020 - ACS Publications
Co-cultivation has been used as a promising tool to turn on or up-regulate cryptic
biosynthetic pathways for microbial natural product discovery. Recently, a modified culturing …

Genome mining for antimicrobial compounds in wild marine animals-associated enterococci

J Prichula, M Primon-Barros, RCZ Luz, ÍMS Castro… - Marine Drugs, 2021 - mdpi.com
New ecosystems are being actively mined for new bioactive compounds. Because of the
large amount of unexplored biodiversity, bacteria from marine environments are especially …

[HTML][HTML] Chemical diversity and biological activities of marine-derived sulphur containing alkaloids: A comprehensive update

Z Zhang, Y Li, Y Sun, W Wang, X Song… - Arabian Journal of …, 2023 - Elsevier
Objectives The ocean is a huge ecosystem with diverse marine life. Scientists have found a
large number of natural products with unique structural features and excellent biological …

The Antitubercular Activities of Natural Products with Fused-Nitrogen-Containing Heterocycles

HI Boshoff, N Malhotra, CE Barry III, S Oh - Pharmaceuticals, 2024 - mdpi.com
Tuberculosis (TB) is notorious as the leading cause of death worldwide due to a single
infectious entity and its causative agent, Mycobacterium tuberculosis (Mtb), has been able to …

Microbial-derived peptides with anti-mycobacterial potential

P Zhao, P Hou, Z Zhang, X Li, C Quan, Y Xue… - European Journal of …, 2024 - Elsevier
Tuberculosis (TB), an airborne infectious disease caused by Mycobacterium tuberculosis,
has become the leading cause of death. The subsequent emergence of multidrug-resistant …

Discovery of Levesquamide B through Global Natural Product Social Molecular Networking

MM LeClair, ZA Maw, AL Grunwald, JR Kelly, BA Haltli… - Molecules, 2022 - mdpi.com
Levesquamide A is an isothiazolinone-containing anti-tubercular natural product isolated
from Streptomyces sp. RKND-216. Through the use of Global Natural Product Social …