Mechanisms of miRNA‐mediated gene regulation from common downregulation to mRNA‐specific upregulation

A Valinezhad Orang, R Safaralizadeh… - … journal of genomics, 2014 - Wiley Online Library
Discovered in 1993, micoRNAs (miRNAs) are now recognized as one of the major
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …

The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

E Mogilyansky, I Rigoutsos - Cell Death & Differentiation, 2013 - nature.com
Abstract The miR-17/92 cluster is among the best-studied microRNA clusters. Interest in the
cluster and its members has been increasing steadily and the number of publications has …

Manipulating microRNA miR408 enhances both biomass yield and saccharification efficiency in poplar

Y Guo, S Wang, K Yu, HL Wang, H Xu, C Song… - Nature …, 2023 - nature.com
The conversion of lignocellulosic feedstocks to fermentable sugar for biofuel production is
inefficient, and most strategies to enhance efficiency directly target lignin biosynthesis, with …

psRNATarget: a plant small RNA target analysis server

X Dai, PX Zhao - Nucleic acids research, 2011 - academic.oup.com
Plant endogenous non-coding short small RNAs (20–24 nt), including microRNAs (miRNAs)
and a subset of small interfering RNAs (ta-siRNAs), play important role in gene expression …

The long noncoding RNA CHRF regulates cardiac hypertrophy by targeting miR-489

K Wang, F Liu, LY Zhou, B Long, SM Yuan… - Circulation …, 2014 - Am Heart Assoc
Rationale: Sustained cardiac hypertrophy is often accompanied by maladaptive cardiac
remodeling leading to decreased compliance and increased risk for heart failure …

MicroRNAs in human cancer

TA Farazi, JI Hoell, P Morozov, T Tuschl - MicroRNA cancer regulation …, 2013 - Springer
Mature microRNAs (miRNAs) are single-stranded RNA molecules of 20–23-nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …

Functions of microRNAs in plant stress responses

R Sunkar, YF Li, G Jagadeeswaran - Trends in plant science, 2012 - cell.com
The discovery of microRNAs (miRNAs) as gene regulators has led to a paradigm shift in the
understanding of post-transcriptional gene regulation in plants and animals. miRNAs have …

microRNAs in Parkinson's disease: from pathogenesis to novel diagnostic and therapeutic approaches

L Leggio, S Vivarelli, F L'Episcopo, C Tirolo… - International journal of …, 2017 - mdpi.com
Parkinson's disease (PD) is the most prevalent central nervous system (CNS) movement
disorder and the second most common neurodegenerative disease overall. PD is …

miRNAs in human cancer

TA Farazi, JI Spitzer, P Morozov… - The Journal of …, 2011 - Wiley Online Library
Mature microRNAs (miRNAs) are single‐stranded RNA molecules of 20–23 nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …

MicroRNA control of signal transduction

M Inui, G Martello, S Piccolo - Nature reviews Molecular cell biology, 2010 - nature.com
MicroRNAs (miRNAs) are integral elements in the post-transcriptional control of gene
expression. After the identification of hundreds of miRNAs, the challenge is now to …