Nanoparticle–cell interactions: molecular structure of the protein corona and cellular outcomes
CC Fleischer, CK Payne - Accounts of chemical research, 2014 - ACS Publications
Conspectus The use of nanoparticles (NPs) in biology and medicine requires a molecular-
level understanding of how NPs interact with cells in a physiological environment. A critical …
level understanding of how NPs interact with cells in a physiological environment. A critical …
Capping gold nanoparticles with albumin to improve their biomedical properties
Nanotechnology is an emerging field which has created great opportunities either through
the creation of new materials or by improving the properties of existing ones. Nanoscale …
the creation of new materials or by improving the properties of existing ones. Nanoscale …
Identifying trends in gold nanoparticle toxicity and uptake: size, shape, capping ligand, and biological corona
The drive behind the growing interest in understanding gold nanoparticle (AuNP) cytotoxicity
originates from the promise of AuNPs for diverse biological applications across the fields of …
originates from the promise of AuNPs for diverse biological applications across the fields of …
Emerging albumin-binding anticancer drugs for tumor-targeted drug delivery: current understandings and clinical translation
Albumin has shown remarkable promise as a natural drug carrier by improving
pharmacokinetic (PK) profiles of anticancer drugs for tumor-targeted delivery. The …
pharmacokinetic (PK) profiles of anticancer drugs for tumor-targeted delivery. The …
Impacts of gold nanoparticle charge and ligand type on surface binding and toxicity to Gram-negative and Gram-positive bacteria
Although nanomaterials facilitate significant technological advancement in our society, their
potential impacts on the environment are yet to be fully understood. In this study, two …
potential impacts on the environment are yet to be fully understood. In this study, two …
Protein-gold nanoparticle interactions and their possible impact on biomedical applications
J Liu, Q Peng - Acta biomaterialia, 2017 - Elsevier
In the past few years, concerns of protein-gold nanoparticles (AuNP) interaction have been
continuously growing in numerous potential biomedical applications. Despite the advances …
continuously growing in numerous potential biomedical applications. Despite the advances …
Secondary structure of corona proteins determines the cell surface receptors used by nanoparticles
CC Fleischer, CK Payne - The Journal of Physical Chemistry B, 2014 - ACS Publications
Nanoparticles used for biological and biomedical applications encounter a host of
extracellular proteins. These proteins rapidly adsorb onto the nanoparticle surface, creating …
extracellular proteins. These proteins rapidly adsorb onto the nanoparticle surface, creating …
Stochastic DNA dual-walkers for ultrafast colorimetric bacteria detection
Rapid, sensitive, and reliable pathogen detection is growing in importance in human health
and safety. In this work, we report a stochastic DNA dual-walker-based colorimetric …
and safety. In this work, we report a stochastic DNA dual-walker-based colorimetric …
Size, shape and surface chemistry of nano-gold dictate its cellular interactions, uptake and toxicity
Colloidal gold is undoubtedly one of the most extensively studied nanomaterials, with 1000s
of different protocols currently available to synthesise gold nanoparticles (AuNPs). While …
of different protocols currently available to synthesise gold nanoparticles (AuNPs). While …
Chiral surface of nanoparticles determines the orientation of adsorbed transferrin and its interaction with receptors
When nanoparticles are exposed to a physiological environment, a “protein corona” is
formed that greatly determines their biological fate. Adsorption of proteins could be …
formed that greatly determines their biological fate. Adsorption of proteins could be …