Photobiology of lipofuscin granules in the retinal pigment epithelium cells of the eye: norm, pathology, age
TB Feldman, AE Dontsov, MA Yakovleva… - Biophysical …, 2022 - Springer
Lipofuscin granules (LGs) are accumulated in the retinal pigment epithelium (RPE) cells.
The progressive LG accumulation can somehow lead to pathology and accelerate the aging …
The progressive LG accumulation can somehow lead to pathology and accelerate the aging …
CFH exerts anti-oxidant effects on retinal pigment epithelial cells independently from protecting against membrane attack complex
C Borras, J Canonica, S Jorieux, T Abache… - Scientific reports, 2019 - nature.com
Abstract Age Related Macular Degeneration (AMD) is the first cause of social blindness in
people aged over 65 leading to atrophy of retinal pigment epithelial cells (RPE) …
people aged over 65 leading to atrophy of retinal pigment epithelial cells (RPE) …
Retinal Pigment Epithelium Pigment Granules: Norms, Age Relations and Pathology
A Dontsov, M Ostrovsky - International Journal of Molecular Sciences, 2024 - mdpi.com
The retinal pigment epithelium (RPE), which ensures the normal functioning of the neural
retina, is a pigmented single-cell layer that separates the retina from the Bruch's membrane …
retina, is a pigmented single-cell layer that separates the retina from the Bruch's membrane …
Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium
MM Nociari, GL Lehmann… - Proceedings of the …, 2014 - National Acad Sciences
Accumulation of lipofuscin bisretinoids (LBs) in the retinal pigment epithelium (RPE) is the
alleged cause of retinal degeneration in genetic blinding diseases (eg, Stargardt) and a …
alleged cause of retinal degeneration in genetic blinding diseases (eg, Stargardt) and a …
Influenza virus Matrix Protein M1 preserves its conformation with pH, changing multimerization state at the priming stage due to electrostatics
EV Shtykova, LA Dadinova, NV Fedorova… - Scientific reports, 2017 - nature.com
Influenza A virus matrix protein M1 plays an essential role in the virus lifecycle, but its
functional and structural properties are not entirely defined. Here we employed small-angle …
functional and structural properties are not entirely defined. Here we employed small-angle …
pH-dependent formation and disintegration of the influenza A virus protein scaffold to provide tension for membrane fusion
OV Batishchev, LA Shilova, MV Kachala… - Journal of …, 2016 - Am Soc Microbiol
Influenza virus is taken up from a pH-neutral extracellular milieu into an endosome, whose
contents then acidify, causing changes in the viral matrix protein (M1) that coats the inner …
contents then acidify, causing changes in the viral matrix protein (M1) that coats the inner …
[HTML][HTML] Voltage-sensitive styryl dyes as singlet oxygen targets on the surface of bilayer lipid membrane
VS Sokolov, AN Gavrilchik, AO Kulagina… - … of Photochemistry and …, 2016 - Elsevier
Photosensitizers are widely used as photodynamic therapeutic agents killing cancer cells by
photooxidation of their components. Development of new effective photosensitive molecules …
photooxidation of their components. Development of new effective photosensitive molecules …
Solution structure, self-assembly, and membrane interactions of the matrix protein from Newcastle disease virus at neutral and acidic pH
EV Shtykova, MV Petoukhov, LA Dadinova… - Journal of …, 2019 - Am Soc Microbiol
Newcastle disease virus (NDV) is an enveloped paramyxovirus. The matrix protein of the
virus (M-NDV) has an innate propensity to produce virus-like particles budding from the …
virus (M-NDV) has an innate propensity to produce virus-like particles budding from the …
Lipid-detergent phase transitions during detergent-mediated liposome solubilization
We investigate the phase transition stages for detergent-mediated liposome solubilization of
bio-mimetic membranes with the motivation of integrating membrane-bound Photosystem I …
bio-mimetic membranes with the motivation of integrating membrane-bound Photosystem I …
Morphological and physiological retinal degeneration induced by intravenous delivery of vitamin A dimers in rabbits
J Penn, DM Mihai, I Washington - Disease Models & …, 2015 - journals.biologists.com
The eye uses vitamin A as a cofactor to sense light and, during this process, some vitamin A
molecules dimerize, forming vitamin A dimers. A striking chemical signature of retinas …
molecules dimerize, forming vitamin A dimers. A striking chemical signature of retinas …