Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

[HTML][HTML] Human aquaporins: regulators of transcellular water flow

RE Day, P Kitchen, DS Owen, C Bland… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Background Emerging evidence supports the view that (AQP) aquaporin water channels are
regulators of transcellular water flow. Consistent with their expression in most tissues, AQPs …

[HTML][HTML] Molecular mechanisms governing aquaporin relocalisation

A Markou, L Unger, M Abir-Awan, A Saadallah… - … et Biophysica Acta (BBA …, 2022 - Elsevier
The aquaporins (AQPs) form a family of integral membrane proteins that facilitate the
movement of water across biological membrane by osmosis, as well as facilitating the …

Beyond water homeostasis: Diverse functional roles of mammalian aquaporins

P Kitchen, RE Day, MM Salman, MT Conner… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Background Aquaporin (AQP) water channels are best known as passive transporters of
water that are vital for water homeostasis. Scope of review AQP knockout studies in whole …

Molecular biology of aquaporins

C Li, W Wang - Aquaporins, 2017 - Springer
Aquaporins (AQPs) are a family of membrane water channels that basically function as
regulators of intracellular and intercellular water flow. To date, thirteen AQPs, which are …

Signaling mechanisms and pharmacological modulators governing diverse aquaporin functions in human health and disease

K Wagner, L Unger, MM Salman, P Kitchen… - International Journal of …, 2022 - mdpi.com
The aquaporins (AQPs) are a family of small integral membrane proteins that facilitate the
bidirectional transport of water across biological membranes in response to osmotic …

Ions, the movement of water and the apoptotic volume decrease

CD Bortner, JA Cidlowski - Frontiers in cell and developmental …, 2020 - frontiersin.org
The movement of water across the cell membrane is a natural biological process that occurs
during growth, cell division, and cell death. Many cells are known to regulate changes in …

Altered expression of AQP1 and AQP4 in brain barriers and cerebrospinal fluid may affect cerebral water balance during chronic hypertension

I González-Marrero, LG Hernández-Abad… - International Journal of …, 2022 - mdpi.com
Hypertension is the leading cause of cardiovascular affection and premature death
worldwide. The spontaneously hypertensive rat (SHR) is the most common animal model of …

Extracellular mechanical forces drive endocardial cell volume decrease during zebrafish cardiac valve morphogenesis

H Vignes, C Vagena-Pantoula, M Prakash, H Fukui… - Developmental cell, 2022 - cell.com
Organ morphogenesis involves dynamic changes of tissue properties while cells adapt to
their mechanical environment through mechanosensitive pathways. How mechanical cues …

Phosphorylation-dependent regulation of mammalian aquaporins

V Nesverova, S Törnroth-Horsefield - Cells, 2019 - mdpi.com
Water homeostasis is fundamental for cell survival. Transport of water across cellular
membranes is governed by aquaporins—tetrameric integral membrane channels that are …