The assay for transposase-accessible chromatin using sequencing (ATAC-seq) provides a
simple and scalable way to detect the unique chromatin landscape associated with a cell …

The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

A mounting body of evidence indicates that dietary fiber (DF) metabolites produced by
commensal bacteria play essential roles in balancing the immune system. DF, considered …

The gastrointestinal tract is continuously exposed to trillions of commensal microbes,
collectively termed the microbiota, which are environmental stimuli that can direct health and …

The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and
ILC3, which participate in immune responses to virus, bacteria, parasites and transformed …

Innate lymphoid cells (ILCs) are lymphocytes that do not express the type of diversified
antigen receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and …

Dendritic cells (DCs) play a critical role in orchestrating adaptive immune responses due to
their unique ability to initiate T cell responses and direct their differentiation into effector …

Alzheimer's disease (AD) is a detrimental neurodegenerative disease with no effective
treatments. Due to cellular heterogeneity, defining the roles of immune cell subsets in AD …

Advances in single-cell RNA sequencing (scRNA-seq) have allowed for comprehensive
analysis of the immune system. In this Review, we briefly describe the available scRNA-seq …

As the intestinal microbiota has become better appreciated as necessary for maintenance of
physiologic homeostasis and also as a modulator of disease processes, there has been a …