Changing views of the pathophysiology of Parkinsonism
T Wichmann - Movement Disorders, 2019 - Wiley Online Library
Studies of the pathophysiology of parkinsonism (specifically akinesia and bradykinesia)
have a long history and primarily model the consequences of dopamine loss in the basal …
have a long history and primarily model the consequences of dopamine loss in the basal …
Clinical implications of local field potentials for understanding and treating movement disorders
JA Thompson, D Lanctin, NF Ince… - Stereotactic and functional …, 2014 - karger.com
Background: Deep brain stimulation (DBS) for the treatment of movement disorders has
provided researchers with an opportunity to record electrical oscillatory activity from …
provided researchers with an opportunity to record electrical oscillatory activity from …
Multimodal modeling of neural network activity: computing LFP, ECoG, EEG, and MEG signals with LFPy 2.0
Recordings of extracellular electrical, and later also magnetic, brain signals have been the
dominant technique for measuring brain activity for decades. The interpretation of such …
dominant technique for measuring brain activity for decades. The interpretation of such …
LFPy: a tool for biophysical simulation of extracellular potentials generated by detailed model neurons
Electrical extracellular recordings, ie, recordings of the electrical potentials in the
extracellular medium between cells, have been a main work-horse in electrophysiology for …
extracellular medium between cells, have been a main work-horse in electrophysiology for …
Field potential 1/f activity in the subcallosal cingulate region as a candidate signal for monitoring deep brain stimulation for treatment-resistant depression
A Veerakumar, V Tiruvadi, B Howell… - Journal of …, 2019 - journals.physiology.org
Subcallosal cingulate cortex deep brain stimulation (SCC-DBS) is an experimental therapy
for treatment-resistant depression (TRD). Refinement and optimization of SCC-DBS will …
for treatment-resistant depression (TRD). Refinement and optimization of SCC-DBS will …
Closing the loop on impulsivity via nucleus accumbens delta-band activity in mice and man
Reward hypersensitization is a common feature of neuropsychiatric disorders, manifesting
as impulsivity for anticipated incentives. Temporally specific changes in activity within the …
as impulsivity for anticipated incentives. Temporally specific changes in activity within the …
[HTML][HTML] Functional connectivity maps of theta/alpha and beta coherence within the subthalamic nucleus region
The subthalamic nucleus (STN) is a primary target for deep brain stimulation in Parkinson's
disease (PD). Although small in size, the STN is commonly partitioned into sensorimotor …
disease (PD). Although small in size, the STN is commonly partitioned into sensorimotor …
[HTML][HTML] Optimal use of EEG recordings to target active brain areas with transcranial electrical stimulation
To demonstrate causal relationships between brain and behavior, investigators would like to
guide brain stimulation using measurements of neural activity. Particularly promising in this …
guide brain stimulation using measurements of neural activity. Particularly promising in this …
Evolving applications, technological challenges and future opportunities in neuromodulation: proceedings of the fifth annual deep brain stimulation think tank
The annual Deep Brain Stimulation (DBS) Think Tank provides a focal opportunity for a
multidisciplinary ensemble of experts in the field of neuromodulation to discuss …
multidisciplinary ensemble of experts in the field of neuromodulation to discuss …
Modelling and analysis of electrical potentials recorded in microelectrode arrays (MEAs)
Abstract Microelectrode arrays (MEAs), substrate-integrated planar arrays of up to
thousands of closely spaced metal electrode contacts, have long been used to record …
thousands of closely spaced metal electrode contacts, have long been used to record …